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品种反应性 主要应用 宿主 格式 抗体类型 R WB M Purified Monoclonal Antibody 描述 产品目录编号 MABS190 描述 Anti-ROS1 Antibody, clone 20C2.1 Alternate Names - c-Ros receptor tyrosine kinase
- Proto-oncogene tyrosine-protein kinase ROS
- Proto-oncogene c-Ros
- Proto-oncogene c-Ros-1
- Receptor tyrosine kinase c-ros oncogene 1
背景信息 Also known as proto-oncogene tyrosine-protein kinase ROS, ROS1 is an orphan receptor tyrosine kinase that belongs to the insulin receptor family. It is highly expressed in the brain, and in primary gliomas. Like other tyrosine kinases, ROS1 phosphorylates a wide range of substrates, including STAT3, VAV3, PTPN11, AKT1, MAPK1, MAPK3, and IRS1, resulting in activation of signaling pathways involved in cell growth, differentiation, proliferation, and survival. 产品信息 格式 Purified 控制 - PC-12 cell lysate
演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-ROS1 Antibody, clone 20C2.1 is an antibody against ROS1 for use in Western Blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human ROS1. 克隆 20C2.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG2aκ 品种反应性 Rat Species Reactivity Note Demonstrated to react with Rat. Predicted to react with Human based on immunogen design. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_002935
基因符号 - ROS
- ROS1
- MCF3
纯化方法 Protein G purified UniProt编号 - P08922
产品使用声明 质量保证 Evaluated by Western Blot in PC-12 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected ROS1 in 10 µg of PC-12 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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