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merck millipore,默克密理博,AB19017,Anti-ADAM 8 Antibody, cytoplasmic domain
产品名称：Anti-ADAM 8 Antibody, cytoplasmic domain
产品型号：AB19017
This Anti-ADAM 8 Antibody, cytoplasmic domain is validated for use in WB for the detection of ADAM 8.
merck millipore,默克密理博,AB19017,Anti-ADAM 8 Antibody, cytoplasmic domain
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Purified Polyclonal Antibody 描述 产品目录编号 AB19017 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-ADAM 8 Antibody, cytoplasmic domain 背景信息 The ADAM (A Disintegrin and Metalloprotease) family of cell surface proteases mediate a number of cellular processes, including differentiation, cell fusion, cell-cell interactions, and shedding of plasma membrane-bound growth factor precursors. Each ADAM contains a prodomain, a catalytic metalloprotease domain, a disintegrin domain, a cysteine-rich domain, a transmembrane domain, and a cytoplasmic domain. ADAM8 was first identified in macrophage cell lines and was designated CD156. Expression of ADAM8 is also observed in osteoclasts, where it promotes osteoclast differentiation. In the CNS during neurodegeneration, ADAM8 is expressed in neurons, astrocytes and microglia. ADAM8 undergoes autocatalytic removal of the prodomain and metalloprotease domain. 产品信息 格式 Purified 控制 - THP-1 lysate
演示 Purified rabbit immunoglobulin in buffer containing 0.1M Tris-Glycine (pH7.4) 15mM NaCl with 0.05% NaN3. 应用 应用 This Anti-ADAM 8 Antibody, cytoplasmic domain is validated for use in WB for the detection of ADAM 8. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated synthetic peptide corresponding to the cytoplasmic domain of human ADAM 8. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 The antibody reacts with the 89 kDa ADAM 8 protein. 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - Cell surface antigen MS2
- CD156a antigen
纯化方法 Antigen affinity purified UniProt编号 - P78325
UniProt汇总 FUNCTION: Possible involvement in extravasation of leukocytes.
COFACTOR: Binds 1 zinc ion per subunit (Probable).
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Expressed on neutrophils and monocytes.
SIMILARITY: Contains 1 disintegrin domain.
SIMILARITY: Contains 1 EGF-like domain.
SIMILARITY: Contains 1 peptidase M12B domain [view classification].产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt. 包装信息 数量 100 µg
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