merck millipore,默克密理愽
  • merck millipore,默克密理博,MABC640,Anti-MUM1 Antibody, clone 4G10

  • merck millipore,默克密理博,MABC640,Anti-MUM1 Antibody, clone 4G10

    产品名称：Anti-MUM1 Antibody, clone 4G10
    产品型号：MABC640
    Detect Mutated melanoma-associated antigen 1 using this mouse monoclonal antibody, Anti-MUM1 Antibody, clone 4G10 validated for use in western blotting & IHC.

    merck millipore,默克密理博,MABC640,Anti-MUM1 Antibody, clone 4G10

  • 产品介绍
  • merck millipore,默克密理博,MABC640,Anti-MUM1 Antibody, clone 4G10

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, WBMAscitesMonoclonal Antibody
    描述
    产品目录编号 MABC640
    描述 Anti-MUM1 Antibody, clone 4G10
    Alternate Names
    • Protein expandere
    • PWWP domain-containing protein MUM1
    • Mutated melanoma-associated antigen 1
    • MUM-1
    背景信息 Mutated melanoma-associated antigen 1 (MUM1), also known as Protein expandere and PWWP domain-containing protein MUM1. MUM1’s normal role is as a DNA and chromatin associated protein that is involved in the cell’s response to DNA damage. It is driven to DNA breaks by its interaction with another DNA chromatin protein, TP53BP1, which it binds. The binding facilitates chromatin relaxation and entry of DNA repair enzymes. MUM1 is required for efficient DNA repair and cellular survival after DNA damage. Interestingly MUM1 was first identified by cloning the chromosomal breakpoints of a multiple myeloma cell line and was identified as a member of the interferon response transcriptional factor gene family (IFR). MUM1 appears to play a critical role in cell proliferation, differentiation and survival of various cancers, as well as monocytes and dendritic cells. MUM1 is expressed in B cells and plasma cells as well and in some populations of T lymphocytes. EMD-Millipore’s Anti-MUM1 mouse monoclonal antibody has been tested in against recombinantly expressed human MUM1 protein and in paraffin embedded immunohistochemistry on human melanoma, non-Hodgkin’s lymphoma and normal uterus tissue sections.
    产品信息
    格式 Ascites
    控制
    • Recombinant MUM1 protein
    演示 Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
    应用
    应用 Detect Mutated melanoma-associated antigen 1 using this mouse monoclonal antibody, Anti-MUM1 Antibody, clone 4G10 validated for use in western blotting & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected MUM1 in human uterus, melanoma, and non-Hodgkin`s lymphoma tissues.

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Purified recombinant fragment of human MUM1 expressed in E. Coli.
    克隆 4G10
    宿主 Mouse
    同种型 IgG1
    品种反应性 Human
    Species Reactivity Note Demonstrated to react with Human.
    抗体类型 Monoclonal Antibody
    基因符号
    • MUM1
    • MUM-1
    • EXPAND1
    纯化方法 Unpurified
    UniProt编号
    • Q2TAK8
    产品使用声明
    质量保证 Evaluated by Western Blotting in recombinant MUM1 protein.

    Western Blotting Analysis: A 1:500-2000 dilution of this antibody detected recombinant MUM1.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MABC640,Anti-MUM1 Antibody, clone 4G10

上一件merck millipore产品：merck millipore,默克密理博,AB9754,Anti-Kisspeptin Antibody
下一件merck millipore产品：merck millipore,默克密理博,MAB5434,Anti-Oct-1 Antibody, clone YL15


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