merck millipore,默克密理愽
  • merck millipore,默克密理博,MABC272,Anti-Annexin VI Antibody, clone 4B11.1

  • merck millipore,默克密理博,MABC272,Anti-Annexin VI Antibody, clone 4B11.1

    产品名称：Anti-Annexin VI Antibody, clone 4B11.1
    产品型号：MABC272
    This Anti-Annexin VI Antibody, clone 4B11.1 is validated for use in western blotting & ICC for the detection of Annexin VI.

    merck millipore,默克密理博,MABC272,Anti-Annexin VI Antibody, clone 4B11.1

  • 产品介绍
  • merck millipore,默克密理博,MABC272,Anti-Annexin VI Antibody, clone 4B11.1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HICC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABC272
    描述 Anti-Annexin VI Antibody, clone 4B11.1
    Alternate Names
    • p70
    • Annexin A6
    • 67 kDa calelectrin
    • Annexin VI
    • Annexin-6
    • Calphobindin-II
    • CPB-II
    • Chromobindin-20
    • Lipocortin VI
    • Protein III
    • p68
    背景信息 The protein Annexin A6 or alternatively known as 67 kDa calelectrin, Annexin VI, Annexin-6, Calphobindin-II (CPB-II), Chromobindin-20, Lipocortin VI, Protein III, p68, or p70 and encoded by the human gene named ANXA6 or ANX6. Annexin VI is part of a large family of Annexin proteins and shares with the family the ability to bind negatively charged phospholipids in a calcium dependent manner. Localized in the plasma membrane annexins are important in many cellular functions as the provide scaffolds and play roles in vesicle transport, exocytosis, endocytosis and calcium transport and conduction. Recent research indicates that Annexin VI can interact with PKCalpha and EGFR in A431 cells to help regulate the phosphorylation of pY-EGFR and the associated activation of downstream signaling events associated with cancer. Annexin VI in normal tissue is expressed most strongly in myocardial tissue where it associates with sarcomeric α-actinin and is part of the sarcomere structure. Annexin VI also regulates terminal chondrocyte differentiation by modulating key signaling pathway activities.
    产品信息
    格式 Purified
    演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 This Anti-Annexin VI Antibody, clone 4B11.1 is validated for use in western blotting & ICC for the detection of Annexin VI.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    应用说明 Western Blotting Analysis: 1 µg/mL from a representative lot detected Annexin VI in 10 µg of C2C12 cell lysate.

    Immunocytochemistry Analysis: A 1:50 dilution from a representative lot detected Annexin VI in HeLa and A431 cells.

    Alexa Fluor® is a registered trademark of Life Technologies®.
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to human Annexin VI.
    克隆 4B11.1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG2aκ
    品种反应性 MouseHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001146
    基因符号
    • ANX6
    • ANXA6
    纯化方法 Protein G purified
    UniProt编号
    • P08133
    产品使用声明
    质量保证 Evaluated by Western Blotting in SH-SY5Y cell lysate.

    Western Blotting Analysis: 0.5 µg/mL of this antibody detected Annexin VI in 10 µg of SH-SY5Y cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABC272,Anti-Annexin VI Antibody, clone 4B11.1

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