merck millipore,默克密理愽
  • merck millipore,默克密理博,382110,Histone Acetyltransferase Inhibitor II - CAS 932749-62-7 - Calbiochem

  • merck millipore,默克密理博,382110,Histone Acetyltransferase Inhibitor II - CAS 932749-62-7 - Calbiochem

    产品名称：Histone Acetyltransferase Inhibitor II - CAS 932749-62-7 - Calbiochem
    产品型号：382110
    The Histone Acetyltransferase Inhibitor II, also referenced under CAS 932749-62-7, controls the biological activity of Histone Acetyltransferase. This small molecule/inhibitor is primarily used for Ce More>>

    merck millipore,默克密理博,382110,Histone Acetyltransferase Inhibitor II - CAS 932749-62-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,382110,Histone Acetyltransferase Inhibitor II - CAS 932749-62-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₀H₁₆Br₂O₃932749-62-7
    描述
    概述 A cell-permeable bis-arylidene cyclohexanone compound that acts as a p300/CBP-selective histone acetyltransferase inhibitor (IC50 = 5 µM), while it affects GCN5 and PCAF only at much higher concentrations (30% and 0% inhibition, respectively, at 5 µM inhibitor concentration). Shown to decrease histone H3 acetylation (IC50 ≤ 40 µM) and induce chromatin condensation in HeLa cells.
    产品目录编号 382110
    品牌系列 Calbiochem®
    同义词 2,6-bis-(3-Bromo-4-hydroxybenzylidene)cyclohexanone, HAT Inhibitor II, p300/CBP Inhibitor II, GCN5 Inhibitor I
    参考
    参考 Costi, R., et al. 2007. J. Med. Chem. 50, 1973.
    产品信息
    CAS号 932749-62-7
    形式 Yellow solid
    Hill配方 C₂₀H₁₆Br₂O₃
    化学配方 C₂₀H₁₆Br₂O₃
    Molar Mass 464.2
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,382110,Histone Acetyltransferase Inhibitor II - CAS 932749-62-7 - Calbiochem

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