merck millipore,默克密理博,MABN1036,Anti-Rab7A Antibody, clone EPR7588(B), rabbit monoclonal

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merck millipore,默克密理博,MABN1036,Anti-Rab7A Antibody, clone EPR7588(B), rabbit monoclonal
产品名称：Anti-Rab7A Antibody, clone EPR7588(B), rabbit monoclonal
产品型号：MABN1036
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.

merck millipore,默克密理博,MABN1036,Anti-Rab7A Antibody, clone EPR7588(B), rabbit monoclonal

产品介绍

merck millipore,默克密理博,MABN1036,Anti-Rab7A Antibody, clone EPR7588(B), rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
M, H, R	IHC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABN1036
描述	Anti-Rab7A Antibody, clone EPR7588(B), rabbit monoclonal
Alternate Names	Rab7a Ras-related protein Rab-7a
背景信息	Ras-related protein Rab-7A (Rab7A, RAB7) is a small intracellular protein typically associated with cytoplasmic vesicles, phagosomes, and endosomes and is expressed in most cells but particularly high in muscle. It plays an important role in regulating the endo-lysosomal trafficking of proteins as well as in the endosomal trapping of pathogens and viruses. Besides endosome-lysosome trafficking, Rab7A functions in a variety of other critical cellular processes including nutrient uptake, growth factor mediated growth, neurotrophin transport, lipid transport, lysosome and phagosome maturation and development, as well as pathogen and virus innate immunity functions. RAB7A interacts with a number of other proteins within the cell, some important in endosome trafficking like RILP (Rab-interacting lysosomal protein) and CHM (Rab escort protein 1) others like RAC1 have a more pleiotropic impact and are part of many cellular processes, including the cell cycle, cell-cell adhesion, cytoskeletal motility, and cellular differentiation. EMD-Millipore’s Anti-Rab7A rabbit monoclonal antibody has been tested in western blot against A375, A431, HACAT, C6, B16-F0 cell lysates and fetal brain tissue lysates and in paraffin embedded immunohistochemistry on human colon adenocarcinoma tissue sections.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:50-100 dilution from a representative lot detected Rab7A in human colon adenocarcinoma tissue. Optimal working dilutions must be determined by end user.

生物信息
免疫原品种	Synthetic peptide corresponding to human Rab7A.
克隆	EPR7588(B)
宿主	Rabbit
品种反应性	MouseHumanRat
抗体类型	Monoclonal Antibody
基因符号	RAB7 RAB7A
纯化方法	Unpurified
UniProt编号	P51149

产品使用声明
质量保证	Evaluated by Western Blotting in A375, A431, HACAT, human fetal brain, B16-F0, and C6 lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected Rab7A in A375, A431, HACAT, human fetal brain, B16-F0, and C6 lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.