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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 06-668 Replaces 04-417 品牌系列 Upstate
商名 - Upstate
描述 Anti-Rsk1/MAPKAP Kinase 1a Antibody 产品信息 格式 Affinity Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide, 5mg/ml BSA before the addition of glycerol to 30% 应用 应用 This Anti-Rsk1/MAPKAP Kinase 1a Antibody is validated for use in IP, WB for the detection of Rsk1/MAPKAP Kinase 1a. 主要应用 - Western Blotting
生物信息 免疫原品种 peptide corresponding to residues 695-708 of mouse Rsk1 and 706-719 of human Rsk1 [CNSSKPTPQLKPIES] 宿主 Rabbit 特异性 Rsk1 同种型 IgG 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_002953
Entrez基因汇总 This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. 基因符号 - RSK1
- RPS6KA1
- HU-1
- RSK-1
- MAPKAPK1A
- RSK
- pp90RSK1
- p90S6K
纯化方法 Immunoaffinity chromatography UniProt编号 - Q15418
UniProt汇总 FUNCTION: SwissProt: Q15418 # Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.
COFACTOR: Magnesium.
SIZE: 735 amino acids; 82723 Da
SUBUNIT: Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation.
PTM: Autophosphorylated on Ser-380, as part of the activation process.
SIMILARITY: SwissProt: Q15418 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 protein kinase domains.产品使用声明 质量保证 routinely evaluated by immunoblot on Rsk1/MAPKAP-K1a from EGF-stimulated A431 RIPA cell lysate 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at -20°C 包装信息 数量 100 µg
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