• merck millipore,默克密理博,428150,Lavendustin A - CAS 125697-92-9 - Calbiochem
  • merck millipore,默克密理博,428150,Lavendustin A - CAS 125697-92-9 - Calbiochem

    产品名称:Lavendustin A - CAS 125697-92-9 - Calbiochem
    产品型号:428150
    A cell-permeable, reversible, and substrate competitive inhibitor of EGF receptor tyrosine kinase and p60c-src with little effect on protein kinase A or protein kinase C.

    merck millipore,默克密理博,428150,Lavendustin A - CAS 125697-92-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,428150,Lavendustin A - CAS 125697-92-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₁H₁₉NO₆125697-92-9
    描述
    概述 A cell-permeable, reversible, and substrate competitive inhibitor of EGF receptor tyrosine kinase (IC50 = 11 nM) and p60c-src (IC50 = 500 nM) with little effect on protein kinase A or protein kinase C (IC50 > 200 µM). Also inhibits NMDA-stimulated cGMP production (IC50 = 30 nM). Exhibits anti-proliferative properties. Suppresses the angiogenic action of vascular endothelial growth factor (VEGF) in rats.
    产品目录编号 428150
    品牌系列 Calbiochem®
    同义词 5-Amino-[(N-2,5-dihydroxybenzyl)-Nʹ-2-hydroxybenzyl]salicylic Acid, RG14355
    参考
    参考 Hu, D.E., and Fan, T.-P. 1995. Br. J. Pharmacol. 114, 262.
    Rodriguez, J., et al. 1994. Neuropharmacology 33, 1267.
    Hsu, C.-Y., et al. 1991. J. Biol. Chem. 266, 21105.
    O’Dell, T.J., et al. 1991. Nature 353, 558; Onoda, T., et al. 1989. J. Nat. Prod. 52, 1252.
    Bishop, J.M. 1983. Annu. Rev. Biochem. 52, 307.
    产品信息
    CAS号 125697-92-9
    具有ATP竞争性 N
    形式 Off-white solid
    Hill配方 C₂₁H₁₉NO₆
    化学配方 C₂₁H₁₉NO₆
    Molar Mass 381.4
    可逆 Y
    结构配方图像
    生物信息
    主靶 EGF receptor tyrosine kinase
    主靶IC50 11 nM and 500 nM against EGF receptor tyrosine kinase and p60c-src, respectively
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 acetic acid, DMSO, or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,428150,Lavendustin A - CAS 125697-92-9 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,420147,JNK Inhibitor XIV, SR-3306 - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,07-2190,Anti-phospho-CAPZIP Antibody (Ser108)



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