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描述 产品目录编号 AG209 品牌系列 Chemicon®
商名 - Chemicon
描述 Vesicular Glutamate Transporter 2, control peptide for AB5907 概述 Synthetic peptide from rat VGLUT2 protein. Alternate Names - VGLUT2
背景信息 Vesicular Glutamate Transporter 2 (VGLUT2) is a sodium dependent inorganic phosphate cotransporter that is involved in the calcium dependent glutamate release from astrocytes. It is expressed in only a subset of neurons, localized to synaptic vesicles, at synapses exhibiting classical excitatory features. VGLUT2 mRNA is found in brain regions that lack VGLUT1, a related protein also displaying sodium dependent inorganic phosphate cotransporter activity. 产品信息 演示 Liquid. 应用 主要应用 - Cell Function Assay
应用说明 For use in blocking the reactivity of AB5907.
Optimal working dilution must be determined by the end user.生物信息 浓缩 1 mg/mL 品种 Rat Entrez基因编号 - NM_020346.1
基因符号 - VGLUT2
- SLC17A6
- DNPI
UniProt编号 - Q9JI12
UniProt汇总 FUNCTION: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. May also mediate the transport of inorganic phosphate.
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein (Potential). Cell junction, synapse, synaptosome.
TISSUE SPECIFICITY: Expressed in brain (at protein level). Expressed in brainstem, deep nuclei, septal nuclei, nuclei of the diagonal band, frontal cortex, hypothalamus, midbrain, parietal cortex and temporal cortex. Also expressed in pineal gland and islets of Langerhans.
SIMILARITY: Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
SIZE: 582 amino acids; 64392 Da产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 3 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µg
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