merck millipore,默克密理愽
  • merck millipore,默克密理博,399275,Nω-Hydroxy-nor-L-arginine, Diacetate Salt - CAS 189302-40-7 - Calbiochem

  • merck millipore,默克密理博,399275,Nω-Hydroxy-nor-L-arginine, Diacetate Salt - CAS 189302-40-7 - Calbiochem

    产品名称：Nω-Hydroxy-nor-L-arginine, Diacetate Salt - CAS 189302-40-7 - Calbiochem
    产品型号：399275
    A potent, selective, competitive, and high affinity inhibitor of arginase.

    merck millipore,默克密理博,399275,Nω-Hydroxy-nor-L-arginine, Diacetate Salt - CAS 189302-40-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,399275,Nω-Hydroxy-nor-L-arginine, Diacetate Salt - CAS 189302-40-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₅H₁₂N₄O₃ · 2CH₃CO₂H189302-40-7
    描述
    概述 A potent, selective, competitive, and high affinity inhibitor of arginase. Shown to inhibit arginase from rat liver (IC50 = 2 µM) and mouse macrophages (IC50 = 50 µM). Shown to specifically interact with the manganese-cluster of the enzyme active site. Does not function as a substrate or as an inhibitor for NOS. Hence, nor-NOHA may be a useful tool to study the interplays between arginase and NOS.
    产品目录编号 399275
    品牌系列 Calbiochem®
    同义词 nor-NOHA, 2CH₃CO₂H, L-2-Amino-(4-(2ʹ-hydroxyguanidino)butyric Acid, 2CH₃CO₂H
    参考
    参考 Gobert, A.P., et al. 2000. Infect. Immun. 68, 4653.
    Meurs, H., et al. 2000. Br. J. Pharmacol. 130, 1793.
    Moali, C., et al. 2000. Biochemistry 39, 8208.
    Tenu, J.P. et al. 1999. Nitric Oxide 3, 427.
    Moali, C., et al. 1998. Biochemistry 37, 10453.
    Custot, J., et al. 1997. J. Am. Chem. Soc. 119, 4086.
    产品信息
    CAS号 189302-40-7
    形式 Off-white solid
    Hill配方 C₅H₁₂N₄O₃ · 2CH₃CO₂H
    化学配方 C₅H₁₂N₄O₃ · 2CH₃CO₂H
    Molar Mass 296.3
    吸湿 Hygroscopic
    结构配方图像
    生物信息
    主靶 arginase from rat liver
    主靶IC50 2 µM
    副靶 mouse macrophages (IC₅₀ = 50 µM)
    纯度 ≥97% by TLC
    理化信息
    溶解度 H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,399275,Nω-Hydroxy-nor-L-arginine, Diacetate Salt - CAS 189302-40-7 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,100109,AACOCF₃ - CAS 149301-79-1 - Calbiochem


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