merck millipore,默克密理愽
  • merck millipore,默克密理博,370625,Guanabenz Acetate - CAS 23256-50-0 - Calbiochem

  • merck millipore,默克密理博,370625,Guanabenz Acetate - CAS 23256-50-0 - Calbiochem

    产品名称：Guanabenz Acetate - CAS 23256-50-0 - Calbiochem
    产品型号：370625
    A cell-permeable α2-adrenoceptor agonist that lowers protein misfolding in stressed cells and acts as a proteostatis regulator.

    merck millipore,默克密理博,370625,Guanabenz Acetate - CAS 23256-50-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,370625,Guanabenz Acetate - CAS 23256-50-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₈H₈Cl₂N₄ • C₂H₄O₂23256-50-0
    描述
    概述 A cell-permeable α2-adrenoceptor agonist that lowers protein misfolding in stressed cells (EC50 ~ 400 nM in tunicamycin treated HeLa cells) and acts as a proteostatis regulator. Shown to selectively bind PPP1R15A/GADD34 and disrupt the PPP1R15A-PP1c complex; sustain eIF2α phosphorylation and increase chaperone availability by attenuating translation.
    产品目录编号 370625
    品牌系列 Calbiochem®
    同义词 1-(2,6-Dichlorobenzylideneamino)guanidine, Acetate, WY-8678
    参考
    参考 Tsaytler, P., et al. 2011. Science 332, 91.
    Erb, S., et al. 2000. Neuropsychopharmacology 23, 138,
    Handley, S.L. and Mithani, S., 1984. Naunyn Schmiedebergs Arch. Pharmacol. 327, 1.
    产品信息
    CAS号 23256-50-0
    形式 White powder
    Hill配方 C₈H₈Cl₂N₄ • C₂H₄O₂
    化学配方 C₈H₈Cl₂N₄ • C₂H₄O₂
    Molar Mass 291.1
    吸湿 Hygroscopic
    结构配方图像
    生物信息
    纯度 ≥99% by HPLC
    理化信息
    溶解度 H₂O
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,370625,Guanabenz Acetate - CAS 23256-50-0 - Calbiochem

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