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merck millipore,默克密理博,ABC347,Anti-Fn14 Antibody
产品名称:Anti-Fn14 Antibody
产品型号:ABC347
Anti-Fn14 Antibody is a highly specific rabbit polyclonal antibody, that targets Fibroblast growth factor 14 & has been tested in western blotting, IHC & Immunofluorescence.
merck millipore,默克密理博,ABC347,Anti-Fn14 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC347 描述 Anti-Fn14 Antibody Alternate Names - FGF-inducible 14
- Fn14 Antibody
- Fibroblast growth factor-inducible 14
- TNFRSF12
- TWEAK-R
背景信息 Fibroblast growth factor 14 (FN14) is a member of the TNF receptor superfamily. FN14 is a receptor for TNFSF12/TWEAK and promotes angiogenesis and the proliferation of endothelial cells. Experiments have shown that FN14 binds to the TNFR-associated factors TRAF1, TRAF2, TRAF3, and TRAF5, suggesting that the signaling pathway induced by TWEAK may be mediated by one or more of these adaptor molecules. Additionally, FN14 is a weak inducer of apoptosis in some cell types and may modulate cellular adhesion to matrix proteins. FN14 is suggested to induce liver regeneration and is highly expressed in hepatocellular carcinomas. Furthermore, TWEAK induces liver progenitor cell proliferation, suggesting FN14 may play a role in hepatocyte growth control and liver neoplasia. FN14 is highly expressed in heart, placenta and kidney. Intermediate expression of FN14 has been recorded in lung, skeletal muscle and pancreas. 产品信息 格式 Affinity Purified 控制 - HepG2 cell lysate
演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-Fn14 Antibody is a highly specific rabbit polyclonal antibody, that targets Fibroblast growth factor 14 & has been tested in western blotting, IHC & Immunofluorescence. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected Fn14 in human liver tissue lysate.
Immunofluorescence Analysis: 20 µg/mL from a representative lot detected Fn14 in human liver tissue.生物信息 免疫原品种 KLH-conjugated Fc-tagged protein corresponding to human Fn14. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - TNFRSF12A
纯化方法 Antigen Affinity purified UniProt编号 - Q9NP84
产品使用声明 质量保证 Evaluated by Western Blotting in HepG2 cell lysate.
Western Blotting Analysis: 4 µg/mL of this antibody detected Fn14 in 15 µg of HepG2 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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