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merck millipore,默克密理博,09-717,Anti-TBX21/T-Bet Antibody
产品名称：Anti-TBX21/T-Bet Antibody
产品型号：09-717
Anti-TBX21/T-Bet Antibody is a Rabbit Polyclonal Antibody for detection of TBX21/T-Bet also known as TBX21, T-Bet, T-box transcription factor, T-box 21 & has been validated in WB.
merck millipore,默克密理博,09-717,Anti-TBX21/T-Bet Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 09-717 品牌系列 Upstate
商名 - Upstate
描述 Anti-TBX21/T-Bet Antibody Alternate Names - T-box 21
- TBX21
- T-Bet
- T-box transcription factor
背景信息 TBX21 (T-box transcription factor, also known as T-Bet) is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Studies in mouse show that TBX21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma. Expression of the human ortholog also correlates with IFN-G expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. TBX21 initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs. Genetic variations in TBX21 are associated with susceptibility to asthma and nasal polyps 产品信息 格式 Affinity Purified 演示 Immunoaffinity purified rabbit IgG in PBS, 0.1% sodium azide, 30% glycerol 应用 应用 Anti-TBX21/T-Bet Antibody is a Rabbit Polyclonal Antibody for detection of TBX21/T-Bet also known as TBX21, T-Bet, T-box transcription factor, T-box 21 & has been validated in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH conjugated synthetic peptide (RYFYPEPGAQDADERR(C) corresponding to a.a. 34-49 of human T-Bet. 表位 a.a. 34-49 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes TBX21/T-Bet 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - 30009
Entrez基因汇总 This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells 纯化方法 Immunoaffinity purified UniProt编号 - Q9UL17
产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
包装信息 数量 100 µg
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