merck millipore,默克密理愽
  • merck millipore,默克密理博,219477,Cdk4 Inhibitor II, NSC 625987 - CAS 141992-47-4 - Calbiochem

  • merck millipore,默克密理博,219477,Cdk4 Inhibitor II, NSC 625987 - CAS 141992-47-4 - Calbiochem

    产品名称：Cdk4 Inhibitor II, NSC 625987 - CAS 141992-47-4 - Calbiochem
    产品型号：219477
    The Cdk4 Inhibitor II, NSC 625987, also referenced under CAS 141992-47-4, controls the biological activity of Cdk4. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylat More>>

    merck millipore,默克密理博,219477,Cdk4 Inhibitor II, NSC 625987 - CAS 141992-47-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,219477,Cdk4 Inhibitor II, NSC 625987 - CAS 141992-47-4 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₅H₁₃NO₂S141992-47-4
    描述
    概述 A thioacridone compound that acts as a reversible and potent substrate-competitive inhibitor of Cdk4/cyclin D1 (IC50 = 200 nM). Displays ~500-fold greater selectivity for Cdk4/cyclin D1 over Cdc2/cyclin A (Cdk1/cyclin A), Cdk2/cyclin A, and Cdk2/cyclin E (IC50 > 100 µM).
    产品目录编号 219477
    品牌系列 Calbiochem®
    同义词 1,4-Dimethoxyacridine-9(10H)-thione
    参考
    参考 Kubo, A., et al. 1999. Clin. Cancer Res. 5, 4279.
    产品信息
    CAS号 141992-47-4
    具有ATP竞争性 N
    形式 Brown solid
    Hill配方 C₁₅H₁₃NO₂S
    化学配方 C₁₅H₁₃NO₂S
    Molar Mass 271.3
    可逆 Y
    结构配方图像
    生物信息
    主靶 CDK4/D1
    主靶IC50 200 nM against CDK4/D1
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,219477,Cdk4 Inhibitor II, NSC 625987 - CAS 141992-47-4 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,UFC801024,Amicon Ultra-4，PLGC Ultracel-PL 超滤膜，10 kDa
下一件merck millipore产品：merck millipore,默克密理博,341205,Etoposide - CAS 33419-42-0 - Calbiochem


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