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merck millipore,默克密理博,341205,Etoposide - CAS 33419-42-0 - Calbiochem
产品名称：Etoposide - CAS 33419-42-0 - Calbiochem
产品型号：341205
A cell-permeable derivative of podophyllotoxin that acts as a topoisomerase II inhibitor (IC₅₀ = 59.2 µM) has major activity against a number of tumors, including germ cell neoplasms, small cell lung More>>
merck millipore,默克密理博,341205,Etoposide - CAS 33419-42-0 - Calbiochem
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重要规格表
经验配方 CAS号 C₂₉H₃₂O₁₃ 33419-42-0 描述 概述 A cell-permeable derivative of podophyllotoxin that acts as a topoisomerase II inhibitor (IC50 = 59.2 µM) has major activity against a number of tumors, including germ cell neoplasms, small cell lung cancer, and malignant lymphoma. Induces apoptosis in mouse thymocytes and in HL-60 human leukemia cells. 产品目录编号 341205 品牌系列 Calbiochem®
同义词 VP-16 参考 参考 De Lange, A.M., et al. 1995. J. Virol. 69, 2082.
Kaufman, S.H., et al. 1993. Cancer Res. 53, 3976.
Onishi, Y., et al. 1993. Biochim. Biophys. Acta 1175, 147.
Terada, T., et al. 1993. J. Med. Chem. 36, 1689.
Wazniak, A.J., et al. 1991. J. Clin. Oncol. 9, 70.
Einhorn, L.H., et al. 1988. J. Clin. Oncol. 6, 451.
Issel, B.F. 1982. Cancer Chemother. Pharmacol. 7, 73.产品信息 CAS号 33419-42-0 具有ATP竞争性 N 形式 White solid Hill配方 C₂₉H₃₂O₁₃ 化学配方 C₂₉H₃₂O₁₃ Molar Mass 588.6 可逆 N 结构配方图像 生物信息 主靶 topoisomerase 2 主靶IC50 59.2 µM inhibiting topoisomerase II 纯度 >97% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO GHS安全信息 RTECS KC0190000 安全信息 R相 R: 22-45
Harmful if swallowed.
May cause cancer.S相 S: 26-36/37/39-45-53
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Avoid exposure - obtain special instructions before use.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Harmful & Carcinogenic / Teratogenic
储存 +15°C to +30°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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