merck millipore,默克密理博,TGFBMAG-64K-03,MILLIPLEX MAP TGFß Magnetic Bead 3 Plex Kit

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Merck Millipore 默克密理愽

merck millipore,默克密理博,TGFBMAG-64K-03,MILLIPLEX MAP TGFß Magnetic Bead 3 Plex Kit - Immunology Multiplex Assay

可用的分析物	品种反应性	主要应用	检测方法
TGF-β3, TGF-β1, TGF-β2	Eq, H, M, R, NhP, Ca, Fe, Po	Mplex	Luminex xMAP

描述
产品目录编号	TGFBMAG-64K-03
商名	MILLIPLEX
描述	MILLIPLEX MAP TGFß Magnetic Bead 3 Plex Kit - Immunology Multiplex Assay
背景信息	The transforming growth factor beta (TGFβ) system, a superfamily of cytokines as well as signaling pathways, is highly conserved throughout the animal kingdom. TGFβ functions in immune cell development, angiogenesis, wound healing and embryonic development, bone development and plays a critical role in immune response, heart disease, and cancer. In its normal state TGFβ is one of the few classes of proteins able to inhibit cell growth by halting mitosis at the G1 state, inducing cell differentiation or apoptosis. However, during oncogenesis mutations in the TGFβ signaling pathway result in tumor cell resistance to the effects of normally functioning TGFβ, causing proliferation without regulation. Initial research suggests that VE-cadherin may enhance the mutated TGFβ signaling pathway.

产品信息
检测方法	Luminex xMAP
配置	Premixed
精度（%）	Intra-assay: < 10 Inter-assay: < 10
板面类型	MAGNETIC Cytokines/Chemokines

应用
应用	This MILLIPLEX MAP TGFß (Transforming Growth Factor Beta) - 3 Plex is an Immunology Multiplex Assay is used for the simultaneous quantification of TGFß1, TGFß2 and TGFß3 in the following species: Mouse/Human/Rat/Pig/Horse/Dog/Cat/Non-Human Primate.
主要应用	Multiplexing
应用说明	• This is a 2-hour or overnight incubation assay. • This assay requires 25 μL of a 1:30 dilution after treatment of serum and plasma samples. • In addition to human, TGFβ1 was detected in acid-activated serum of every species tested which included horse, rabbit, mouse, rat, mini pig, canine, hamster, guinea pig, rhesus monkey and cynomolgous monkey. In addition to human, TGFβ2 was detected in the acid-activated serum of the following: horse, rabbit, mouse, rat, mini pig, canine, hamster, guinea pig, rhesus monkey and cynomolgous monkey. In addition to human, TGFβ3 was detected in mouse, rat, mini pig, hamster, guinea pig, rhesus monkey and cynomolgous monkey samples. However, the exact amount of cross reactivity has not been determined.

生物信息
特异性	Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
品种反应性	HorseHumanMouseRatNon-human PrimateCanineFelinePig
可用的分析物	TGF-β3 TGF-β1 TGF-β2
化验面板	Premixed beads for your convenience.
准确度	62% - 128%

理化信息
灵敏度	8 - 12 pg/mL
标准曲线范围	9.8 - 2,500 pg/mL

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Recommended storage for kit components is 2 - 8°C.

包装信息
数量	96-well plate

merck millipore,默克密理博,TGFBMAG-64K-03,MILLIPLEX MAP TGFß Magnetic Bead 3 Plex Kit - Immunology Multiplex Assay

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