• merck millipore,默克密理博,529505,PON1 Activator, ZNPA - Calbiochem
  • merck millipore,默克密理博,529505,PON1 Activator, ZNPA - Calbiochem

    产品名称:PON1 Activator, ZNPA - Calbiochem
    产品型号:529505
    The PON1 Activator, ZNPA modulates the biological activity of PON1. This small molecule/inhibitor is primarily used for Biochemicals applications.

    merck millipore,默克密理博,529505,PON1 Activator, ZNPA - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,529505,PON1 Activator, ZNPA - Calbiochem

    重要规格表

    经验配方
    C₁₅H₉N₃O₄
    描述
    概述 A cell-permeable stilbene derivative that serves as an aryl hydrocarbon receptor (AhR) ligand and acts as a highly specific and potent inducer of paraoxonase 1 (PON1). Shown to be a better activator of PON1 mRNA (EC50 = 1 µM) and inducer of PON1 enzymatic activity (> 3 fold at 5 µM) when compared to resveratrol (Cat. No. 554325). However, it is devoid of any activity against estrogen receptors and is not shown to inhibit activity of tyrosine kinases. Also shown to antagonize the effects of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) on cytochrome P450 1A1 (CYP1A1).
    产品目录编号 529505
    品牌系列 Calbiochem®
    同义词 (Z)-2,3-bis (4-nitrophenyl)-acrylonitrile
    参考
    参考 Guyot, E., et al. 2011. Biochem. Pharm. 83, 627.
    产品信息
    形式 Pale yellow solid
    Hill配方 C₁₅H₉N₃O₄
    化学配方 C₁₅H₉N₃O₄
    Molar Mass 295.3
    结构配方图像
    生物信息
    纯度 ≥99% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,529505,PON1 Activator, ZNPA - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,GF051,Granulocyte Colony-Stimulating Factor Protein, Recombinant human
下一件merck millipore产品:merck millipore,默克密理博,176908,Anthrax Protective Antigen, Bacillus anthracis, Nicked, Recombinant, B. anthracis - Calbiochem



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