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Replacement Information Replacement Information AB1768-I is a recommended replacement for AB1768-25UG 重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H, M, R WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB1768-I Replaces AB1768-25UG 描述 Anti-GluR2 Antibody Alternate Names - GluA2
- Glutamate receptor 2
- GluR-2
- AMPA-selective glutamate receptor 2
- GluR-B
- GluR-K2
- Glutamate receptor ionotropic
- AMPA 2
背景信息 Glutamate receptors (GluRs) can be categorized as ionotropic or metabotropic and subcatergorized by their agonist preferences (NMDA, AMPA or Kainic acid). There are four types of AMPA selective GluR subunits (GluR1, GluR2, GluR3 and GluR4). Tetrameric or pentameric combinations of different subunits contributes to the functional diversity of AMPA receptors. In general, AMPA receptors mediate fast synaptic current at most excitatory synapses, with stoichiometry characterized by subtype composition. Although subunit composition of AMPA receptors varies, they must contain at least one edited GluR2 subunit to be calcium impermeable. Relative calcium permeability in AMPA receptor channels may be significant in pathological neurotoxic damage and long term changes in nervous system responses. 产品信息 格式 Affinity Purified 控制 - Mouse brain tissue lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This GluR2 antibody is validated for use in WB & IHC for the detection of the GluR2 protein. 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:4,000 dilution from a representative lot detected GluR2 in normal human and rat brain tissues. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the cytoplasmic domain of rat GluR2. 表位 Cytoplasmic domain 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes the cytoplasmic domain of Glutamate Receptor 2. 品种反应性 HumanMouseRat Species Reactivity Note Demonstrated to react with Mouse, Rat, and Human. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_058957
基因符号 - Glur2
- Gria2
纯化方法 Affinity purified UniProt编号 - P19491
产品使用声明 质量保证 Evaluated by Western Blotting in mouse brain tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected GluR2 in 10 µg of mouse brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 25 µg
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