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merck millipore,默克密理博,MABN604,Anti-LAR/PTPRF Antibody, clone N165/38
产品名称：Anti-LAR/PTPRF Antibody, clone N165/38
产品型号：MABN604
Anti-LAR/PTPRF Antibody, clone N165/38 is a highly specific mouse monoclonal antibody & that targets LAR & has been tested in western blotting.
merck millipore,默克密理博,MABN604,Anti-LAR/PTPRF Antibody, clone N165/38
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R WB M Purified Monoclonal Antibody 描述 产品目录编号 MABN604 描述 Anti-LAR/PTPRF Antibody, clone N165/38 Alternate Names - LAR
- Receptor-type tyrosine-protein phosphatase F
- Leukocyte common antigen related
背景信息 Receptor-linked protein-tyrosine phosphatases (RPTPs) are signaling proteins that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. Leukocyte common antigen receptor protein tyrosine phosphatase (LAR/PTPRF), a negative regulator of several receptor tyrosine kinases, is present in high concentrations in mature synapses and is considered to be important for the development and maintenance of excitatory synapses in hippocampal neurons. Disruption of LAR function is shown to result in loss of excitatory synapses, diminution in surface AMPA receptors, and impairment of dendritic targeting of the cadherin–beta-catenin complex. LAR is also present in neurons expressing TrkB where it participates in survival of neurons and the neurite outgrowth. Increased expression of LAR in insulin-responsive tissues has also been associated with obesity and insulin resistance. 产品信息 格式 Purified 控制 - Rat brain membrane tissue
演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-LAR/PTPRF Antibody, clone N165/38 is a highly specific mouse monoclonal antibody & that targets LAR & has been tested in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 Recombinant protein corresponding to human LAR/PTPRF. 克隆 N165/38 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody does not cross-react with PTPRD and PTPRS (Prof. J. Trimmer, University of California, Davis.). 同种型 IgG2aκ 品种反应性 Rat Species Reactivity Note Demonstrated to react with Rat. Other Homologies: Mouse (97% sequence homology). 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_002831
基因符号 - LAR
- PTPRF
纯化方法 Protein G purified UniProt编号 - P10586
产品使用声明 质量保证 Evaluated by Western Blotting in rat brain membrane tissue.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected LAR/PTPRF in 10 µg of rat brain membrane tissue.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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