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描述 产品目录编号 14-278 品牌系列 Upstate
商名 - Upstate
描述 Ras Assay Reagent (Raf-1 RBD, agarose) 概述 GST fusion-protein, corresponding to Ras Binding Domain of Raf-1, provided bound to glutathione agarose. 应用 主要应用 - Enzyme Assay
生物信息 来源 Human Ras Binding Domain (RBD, residues 1-149) of Raf-1, expressed in E. coli. 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_012219.3
- NM_001085049.1
Entrez基因汇总 Members of the RAS superfamily of GTP-binding proteins, which includes MRAS, are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors.[supplied by OMIM] 基因符号 - M-RAs
- MRAS
- RRAS3
- M-RAS
- FLJ42964
- R-RAS3
UniProt编号 - O14807
UniProt汇总 FUNCTION: SwissProt: O14807 # May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway.
SIZE: 208 amino acids; 23846 Da
SUBUNIT: Interacts with RGL3 (By similarity).
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential).
TISSUE SPECIFICITY: Expression highly restricted to the brain and heart.
SIMILARITY: SwissProt: O14807 ## Belongs to the small GTPase superfamily. Ras family.产品使用声明 质量保证 Routinely evaluated by Affinity Precipitation/Immunoblot Analysis 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at -20°C 包装信息 数量 600 µg
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