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merck millipore,默克密理博,MABT470,Anti-DSG3, clone EPR7420, Rabbit Monoclonal Antibody
产品名称:Anti-DSG3, clone EPR7420, Rabbit Monoclonal Antibody
产品型号:MABT470
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.
merck millipore,默克密理博,MABT470,Anti-DSG3, clone EPR7420, Rabbit Monoclonal Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Unpurified Monoclonal Antibody 描述 产品目录编号 MABT470 描述 Anti-DSG3, clone EPR7420, Rabbit Monoclonal Antibody Alternate Names - Cadherin family member 6
- Desmoglein-3
- 130 kDa pemphigus vulgaris antigen
- PVA
背景信息 Desmoglein-3, also known as 130 kDa pemphigus vulgaris antigen (PVA) or Cadherin family member 6, and encoded by the gene name DSG3, is involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. DSG3 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. 产品信息 格式 Unpurified 演示 Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol. 应用 应用 Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. 主要应用 - Western Blotting
应用说明 Produced in collaboration with Epitomics™ 生物信息 免疫原品种 Synthetic peptide corresponding to human DSG3. 克隆 EPR7420 浓缩 Please refer to lot specific datasheet. 宿主 Rabbit 同种型 IgG 品种反应性 Human Species Reactivity Note Human 抗体类型 Monoclonal Antibody 基因符号 - CDHF6
- DSG3
纯化方法 Unpurified UniProt编号 - P32926
产品使用声明 质量保证 Evaluated by Western Blotting in human tonsil tissue and A431 cell lysates.
Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected DSG3 in human tonsil tissue and A431 cell lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 100 µL
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