merck millipore,默克密理愽
  • merck millipore,默克密理博,197223,Bcr-abl Inhibitor II - CAS 607702-99-8 - Calbiochem

  • merck millipore,默克密理博,197223,Bcr-abl Inhibitor II - CAS 607702-99-8 - Calbiochem

    产品名称：Bcr-abl Inhibitor II - CAS 607702-99-8 - Calbiochem
    产品型号：197223
    The Bcr-abl Inhibitor II, also referenced under CAS 607702-99-8, controls the biological activity of Bcr-abl. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation ap More>>

    merck millipore,默克密理博,197223,Bcr-abl Inhibitor II - CAS 607702-99-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,197223,Bcr-abl Inhibitor II - CAS 607702-99-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆H₁₁F₂N₃OS₂607702-99-8
    描述
    概述 A cell-permeable thiadiazole compound that acts as an ATP binding site-targeting inhibitor of Abl and c-Src kinases (Ki = 44 and 354 nM, respectively). Effectively inhibits cellular Bcr-Abl Tyr245 phosphorylation and the clonogenic activity of Bcr-Abl-transformed 32D cells, regardless of their resistance to Imatinib/STI571.
    产品目录编号 197223
    品牌系列 Calbiochem®
    同义词 5-[(4-fluorobenzoyl)amino]-2-[(4-fluorobenzyl)thio]-1,3,4-thiadiazole, Abl Inhibitor II
    参考
    参考 Radi, M., et al. 2008. Bioorg. Med. Chem. Lett. 18, 1207.
    产品信息
    CAS号 607702-99-8
    形式 White solid
    Hill配方 C₁₆H₁₁F₂N₃OS₂
    化学配方 C₁₆H₁₁F₂N₃OS₂
    Molar Mass 363.4
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,197223,Bcr-abl Inhibitor II - CAS 607702-99-8 - Calbiochem

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