merck millipore,默克密理博,MABN1045,Anti-ACBD3 Antibody, clone EPR8623, rabbit monoclonal

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merck millipore,默克密理博,MABN1045,Anti-ACBD3 Antibody, clone EPR8623, rabbit monoclonal
产品名称：Anti-ACBD3 Antibody, clone EPR8623, rabbit monoclonal
产品型号：MABN1045
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.

merck millipore,默克密理博,MABN1045,Anti-ACBD3 Antibody, clone EPR8623, rabbit monoclonal

产品介绍

merck millipore,默克密理博,MABN1045,Anti-ACBD3 Antibody, clone EPR8623, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	FC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABN1045
描述	Anti-ACBD3 Antibody, clone EPR8623, rabbit monoclonal
Alternate Names	Peripheral benzodiazepine receptor-associated protein PAP7 Golgi resident protein GCP60 Acyl-CoA-binding domain-containing protein 3 Golgi complex-associated protein 1 GOCAP1<br />Golgi phosphoprotein 1 GOLPH1 PBR- and PKA-associated protein 7
背景信息	Golgi resident protein GCP60 or alternatively named ACBD3, (Acyl-CoA-binding domain-containing protein 3), or Golgi complex-associated protein 1 (GOCAP1), Golgi phosphoprotein 1 (GOLPH1), PBR-and PKA-associated protein 7 (PAP7), Peripheral benzodiazepine receptor-associated protein PAP7 is encoded by the human gene named ACBD3, GCP60, GOCAP1, or GOLPH1 and is a major component of Golgi structure and assists in the maintenance of the Golgi by interacting with another Golgi protein giantin. ACBD3 also helps regulate the protein transport between the Golgi and endoplasmic reticulum, and in cells such as the Leydig cells of the testis it assists in the secretion and synthesis of steroids and lipid biosynthesis. It is found largely in the Golgi apparatus and membranes but can be found in the mitochondria as well. ACBD3 is expressed in most tissues, with the highest levels being in the testis and ovary. ACBD3 also plays critical roles in assisting the operation of other signaling pathways as well such as the regulation of PPM1L in the trafficking of ceraminde in the Golgi, and ACBD3 appears to have biological roles in steroidogenesis, apoptosis, neurogenesis, and embryogenesis. EMD-Millipore’s Anti-ACBD3 rabbit monoclonal has been tested in western blot on K562, HeLa, 293T, and LNCaP cell lysates and flow cytometry on permeabilized K562 cells in culture.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.
主要应用	Flow Cytometry Western Blotting
应用说明	Flow Cytometry Analysis: A 1:100-500 dilution from a representative lot detected ACBD3 in K562 cells. Optimal working dilutions must be determined by end user.

生物信息
免疫原品种	Synthetic peptide corresponding to human ACBD3.
克隆	EPR8623
宿主	Rabbit
品种反应性	Human
抗体类型	Monoclonal Antibody
基因符号	GOLPH1 ACBD3 GCP60 GOCAP1
纯化方法	Unpurified
UniProt编号	Q9H3P7

产品使用声明
质量保证	Evaluated by Western Blotting in K562, HeLa, HEK293, and LNCaP cell lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected ACBD3 in K562, HeLa, HEK293, and LNCaP cell lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.