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merck millipore,默克密理博,444274,MMP-2/MMP-9 Inhibitor IV - CAS 292605-14-2 - Calbiochem
产品名称：MMP-2/MMP-9 Inhibitor IV - CAS 292605-14-2 - Calbiochem
产品型号：444274
The MMP-2/MMP-9 Inhibitor IV, also referenced under CAS 292605-14-2, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applicatio More>>
merck millipore,默克密理博,444274,MMP-2/MMP-9 Inhibitor IV - CAS 292605-14-2 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₅H₁₄O₃S₂ 292605-14-2 描述 概述 A potent, selective, slow-binding and mechanism-based inhibitor of human gelatinases, MMP-2 (Ki = 13.9 nM), and MMP-9 (Ki = 600 nM). This inhibitor appears to behave similarly to TIMP-1 and TIMP-2 in the slow-binding component of inhibition. Also exhibits a covalent mechanism-based behavior in inhibition of these enzymes. Binds directly to the catalytic zinc ion on MMP-2. 产品目录编号 444274 品牌系列 Calbiochem®
同义词 SB-3CT 参考 参考 Krüger, A., et al. 2005. Cancer Res. 65, 3523.
Kleinfeld, O., et al. 2001. J. Biol. Chem. 276, 17125.
Brown, S., et al. 2000. J. Am. Chem. Soc. 122, 6799.产品信息 CAS号 292605-14-2 具有ATP竞争性 N 声明 Sold under license of U.S. Patent 6,703,415. 形式 Off-white solid Hill配方 C₁₅H₁₄O₃S₂ 化学配方 C₁₅H₁₄O₃S₂ Molar Mass 306.4 可逆 N 结构配方图像 生物信息 主靶 MMP-2 主靶Ki 13.9 nM 纯度 ≥ 95% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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