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merck millipore,默克密理博,MABE116,Anti-SRp20 Antibody, clone 7B4
产品名称:Anti-SRp20 Antibody, clone 7B4
产品型号:MABE116
Anti-SRp20 Antibody, clone 7B4 is a Mouse Monoclonal Antibody for detection of SRp20 also known as splicing factor arginine/serine-rich 3 & has been validated in WB & ICC.
merck millipore,默克密理博,MABE116,Anti-SRp20 Antibody, clone 7B4
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M ICC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABE116 描述 Anti-SRp20 Antibody, clone 7B4 Alternate Names - splicing factor, arginine/serine-rich, 20-kD
- splicing factor, arginine/serine-rich 3
- Pre-mRNA-splicing factor SRP20
背景信息 Splicing factor, arginine/serine-rich 3 (SRp20) is a member of the splicing factor SR family and contains an RRP (RNA recognition motif) domain. SRp20 has been shown as being localized to nuclear sites of RNA transcription and localization of SR protein. It is involved in mediating RNA export in association with the proliferation and/or maturation of cells. SRp20 has also been implicated in recent studies as having a regulatory role in the early-to-late switch of Papillomavirus, and as being target for the regulation of splicing modifications by the β-catenin/TCF4 pathway. Up-regulation of SRp20 has also been linked with malignant epithelial ovarian cancer. 产品信息 格式 Purified 控制 - HeLa nuclear extract
演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-SRp20 Antibody, clone 7B4 is a Mouse Monoclonal Antibody for detection of SRp20 also known as splicing factor arginine/serine-rich 3 & has been validated in WB & ICC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in IC (Neugebauer, K.M. , et al., 1997). 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human SRp20. 克隆 7B4 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with human.
Predicted to react with mouse and rat based on 100% sequence homology.抗体类型 Monoclonal Antibody Entrez基因编号 - NP_003008
基因符号 - SFRS3
- SRp20
纯化方法 Protein G Purified UniProt编号 - P84103
UniProt汇总 FUNCTION: May be involved in RNA processing in relation with cellular proliferation and/or maturation.
SUBUNIT STRUCTURE: Interacts with CPSF6, RBMY1A1 and SFRS12.
SUBCELLULAR LOCATION: Nucleus.
PTM: Extensively phosphorylated on serine residues in the RS domain (By similarity).
SEQUENCE SIMILARITIES: Belongs to the splicing factor SR family.
Contains 1 RRM (RNA recognition motif) domain.产品使用声明 质量保证 Evaluated by Western Blot in HeLa nuclear extract.
Western Blot Analysis: 0.5 µg/mL of this antibody detected SRp20 in 10 µg of HeLa nuclear extract.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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