- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,MAB88916,Anti-Fibronectin Frag Antibody, cell attachment fragment, clone 3E3
产品名称：Anti-Fibronectin Frag Antibody, cell attachment fragment, clone 3E3
产品型号：MAB88916
Anti-Fibronectin Frag Antibody, cell attachment fragment, clone 3E3 is an antibody against Fibronectin Frag for use in ELISA, WB, IC, IH.
merck millipore,默克密理博,MAB88916,Anti-Fibronectin Frag Antibody, cell attachment fragment, clone 3E3
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, ELISA, WB, ICC M Purified Monoclonal Antibody 描述 产品目录编号 MAB88916 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Fibronectin Frag Antibody, cell attachment fragment, clone 3E3 产品信息 格式 Purified 演示 Purified immunoglobulin. Liquid in 0.02M Phosphate buffer, 0.25M NaCl with 0.1% sodium azide. 应用 应用 Anti-Fibronectin Frag Antibody, cell attachment fragment, clone 3E3 is an antibody against Fibronectin Frag for use in ELISA, WB, IC, IH. 主要应用 - Immunohistochemistry
- ELISA
- Western Blotting
- Immunocytochemistry
应用说明 Immunocytochemistry: (5-20 μg/mL) Immunohistochemistry: (5-20 μg/mL) (Not tested on paraffin sections) Immunoblotting: (5-20 μg-mL)
ELISA
Inactivation or inhibition studies in cell culture.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Purified human-fibronectin from amnion liquid. 表位 cell attachment fragment 克隆 3E3 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 The antibody reacts with human fibronectin and with a peptic fragment (11.5 kD) from human fibronectin (Pierschbacker et al., 1981) comprimising the cell attachment site (Pierschbacker et al., 1981; Pierschabacker et al., 1983, 1984; Hayman et al., 1985; Ruoslahti et al., 1986; Hynes, 1985). It inhibits the attachment of normal rat kidney cells to human fironectin coated plastic surface (Pierschbacker et al., 1981). Binding of the antibody to fibronectin cannot be inhibited by cell adhesion peptides from fibronectin having the sequence Arg-Gly-Asp of Gly-Arg-Gly-Asp-Ser (Pierschabacker et al., 1984; Hayman et al., 1985; Ruoslahti et al., 1986). 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_212482.1
- NM_002026.2
- NM_054034.2
- NM_212474.1
- NM_212475.1
- NM_212476.1
- NM_212478.1
Entrez基因汇总 This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. 基因符号 - FINC
- FN1
- DKFZp686H0342
- DKFZp686I1370
- MSF
- CIG
- LETS
- DKFZp686O13149
- FN
- DKFZp686F10164
UniProt编号 - P02751
UniProt汇总 FUNCTION: SwissProt: P02751 # Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Interaction with TNR mediates inhibition of cell adhesion and neurite outgrowth (By similarity).
SIZE: 2386 amino acids; 262607 Da
SUBUNIT: Mostly heterodimers or multimers of alternatively spliced variants, connected by 2 disulfide bonds near the carboxyl ends; to a lesser extent homodimers. Interacts with FBLN1, AMBP, TNR, LGALS3BP and COL13A1.
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.
TISSUE SPECIFICITY: Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.DEVELOPMENTAL STAGE: Ugl-Y1, Ugl-Y2 and Ugl-Y3 are present in the urine from 0 to 17 years of age.
PTM: Sulfated.
SIMILARITY: SwissProt: P02751 ## Contains 12 fibronectin type-I domains. & Contains 2 fibronectin type-II domains. & Contains 16 fibronectin type-III domains.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,HTS176RTA,Ready-to-Assay™ S1P1 Lysophospholipid Receptor Frozen Cells
下一件merck millipore产品：merck millipore,默克密理博,DR1071,Anti-TFAM Rabbit pAb
相关产品
merck millipore,默克密理博,344281,Forskolin, NKH477 - CAS 138605-00-2 - Calbiochem
merck millipore,默克密理博,PF117,MT5-MMP, Catalytic Domain, His•Tag, Human, Recombinant, E. coli
merck millipore,默克密理博,676493,VEGF Inhibitor, Flt₂₋₁₁ - Calbiochem
merck millipore,默克密理博,HTS176RTA,Ready-to-Assay™ S1P1 Lysophospholipid Receptor Frozen Cells
merck millipore,默克密理博,DR1071,Anti-TFAM Rabbit pAb
merck millipore,默克密理博,ABN39,Anti-Ceruloplasmin (CP) Antibody
merck millipore,默克密理博,SF-2410,CACNA1G; Human, Cyanine 5 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,ABT98,Anti-Kinectin Antibody
merck millipore,默克密理博,ABN374,Anti-phospho-PTEN Antibody (Thr366)