• merck millipore,默克密理博,PF117,MT5-MMP, Catalytic Domain, His•Tag, Human, Recombinant, E. coli
  • merck millipore,默克密理博,PF117,MT5-MMP, Catalytic Domain, His•Tag, Human, Recombinant, E. coli

    产品名称:MT5-MMP, Catalytic Domain, His•Tag, Human, Recombinant, E. coli
    产品型号:PF117


    merck millipore,默克密理博,PF117,MT5-MMP, Catalytic Domain, His•Tag, Human, Recombinant, E. coli

  • 产品介绍
  • merck millipore,默克密理博,PF117,MT5-MMP, Catalytic Domain, His•Tag, Human, Recombinant, E. coli

    重要规格表

    描述
    概述 Recombinant, human pro-MT5-MMP fused to a His•Tag® sequence, expressed in E. coli and activated to yield the active catalytic domain. Two isoforms are produced, one with an N-terminal Tyr156, the other with an N-terminal Leu158. Useful for the study of the activation of progelatinase A and the degradation of extracellular matrix proteins. MT5-MMP is a member of the Zn2+- and Ca2+-dependent endopeptidases that functions in the degradation of extracellular matrix components such as gelatin, chondroitin sulfate, and dermatan sulfate. It has a tendency to be shed from cell surface membranes and appears to undergo rapid autocatalytic destruction into smaller fragments.
    产品目录编号 PF117
    品牌系列 Calbiochem®
    同义词 MMP-24, Catalytic Domain
    参考
    参考 Llano, E., et al. 1999. Cancer Res. 59, 2570.
    Pei, D. 1999. J. Biol. Chem. 274, 8925.
    产品信息
    形式 Liquid
    配方 In 150 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, pH 7.5.
    Molar Mass 22,000
    防腐剂 None
    生物信息
    纯度 ≥95% by SDS-PAGE
    特异活性 ≥100 mU/mg protein
    浓缩标签 Please refer to vial label for lot-specific concentration
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Standard Handling
    储存 ≤ -70°C
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-70°C).

    merck millipore,默克密理博,PF117,MT5-MMP, Catalytic Domain, His•Tag, Human, Recombinant, E. coli

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