merck millipore,默克密理愽
  • merck millipore,默克密理博,AB1247,Anti-Cytochrome P450 Enzyme CYP1A1 Antibody

  • merck millipore,默克密理博,AB1247,Anti-Cytochrome P450 Enzyme CYP1A1 Antibody

    产品名称：Anti-Cytochrome P450 Enzyme CYP1A1 Antibody
    产品型号：AB1247
    Detect Cytochrome P450 Enzyme CYP1A1 using this Anti-Cytochrome P450 Enzyme CYP1A1 Antibody validated for use in IH & WB.

    merck millipore,默克密理博,AB1247,Anti-Cytochrome P450 Enzyme CYP1A1 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB1247,Anti-Cytochrome P450 Enzyme CYP1A1 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RWB, IHCRbSerumPolyclonal Antibody
    描述
    产品目录编号 AB1247
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Cytochrome P450 Enzyme CYP1A1 Antibody
    产品信息
    格式 Serum
    控制
    • Liver tissue
    演示 Rabbit antiSerum. Liquid containing no preservative
    应用
    应用 Detect Cytochrome P450 Enzyme CYP1A1 using this Anti-Cytochrome P450 Enzyme CYP1A1 Antibody validated for use in IH & WB.
    主要应用
    • Western Blotting
    • Immunohistochemistry
    应用说明 Western blot

    Immunohistochemistry on frozen and formaldehyde treated sections.

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Synthetic peptide
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Reacts with rat cytochrome P450 enzyme CYP1A1 in hepatic microsomal fraction. No cross-reactivity with other cytochrome P450 enzymes including CYP1A2.
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_000499.2
    Entrez基因汇总 This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
    基因符号
    • AHH
    • CYP1A1
    • CP11
    • P1-450
    • CYPIA1
    • P450-C
    • CYP1
    • P450DX
    • P450-P1
    • AHRR
    纯化方法 Unpurified
    UniProt编号
    • P04798
    UniProt汇总 FUNCTION: SwissProt: P04798 # Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
    SIZE: 512 amino acids; 58165 Da
    SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
    TISSUE SPECIFICITY: Lung, lymphocytes and placenta.
    SIMILARITY: SwissProt: P04798 ## Belongs to the cytochrome P450 family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,AB1247,Anti-Cytochrome P450 Enzyme CYP1A1 Antibody

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