merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB3564,Anti-Sodium/Iodine Symporter Antibody, a.a. 625-643, clone FP5A

  • merck millipore,默克密理博,MAB3564,Anti-Sodium/Iodine Symporter Antibody, a.a. 625-643, clone FP5A

    产品名称：Anti-Sodium/Iodine Symporter Antibody, a.a. 625-643, clone FP5A
    产品型号：MAB3564
    Detect Sodium/Iodine Symporter using this Anti-Sodium/Iodine Symporter Antibody, a.a. 625-643, clone FP5A validated for use in IH, IH(P) & WB.

    merck millipore,默克密理博,MAB3564,Anti-Sodium/Iodine Symporter Antibody, a.a. 625-643, clone FP5A

  • 产品介绍
  • merck millipore,默克密理博,MAB3564,Anti-Sodium/Iodine Symporter Antibody, a.a. 625-643, clone FP5A

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWB, IHCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB3564
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Sodium/Iodine Symporter Antibody, a.a. 625-643, clone FP5A
    Alternate Names
    • NIS
    • Na+/I- Symporter
    产品信息
    格式 Purified
    演示 Liquid. Buffer = 0.02M Phosphate buffer, 0.25M NaCl with 0.1% sodium azide.
    应用
    应用 Detect Sodium/Iodine Symporter using this Anti-Sodium/Iodine Symporter Antibody, a.a. 625-643, clone FP5A validated for use in IH, IH(P) & WB.
    主要应用
    • Western Blotting
    • Immunohistochemistry
    应用说明 Immunoblotting. The antibody recognizes a major band at ~97 kDa and minor bands at 15 kDa, 30 kDa, 68 kDa and 160 kDa.

    Immunohistochemistry. The antibody works on paraffin embedded tissue sections which have been subjected to antigen retrieval with 10 mM citrate buffer steam for 30 minutes.

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Maltose Binding Protein fusion protein corresponding to amino acids 468-643 of human NIS (C-terminus).
    表位 a.a. 625-643
    克隆 FP5A
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Sodium/Iodide Symporter (NIS). The epitope is thought to be in the region of amino acids 625-643 of human NIS. The antibody may show some reactivity to Maltose Binding Protein.
    同种型 IgG1κ
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_000453.1
    Entrez基因汇总 The sodium-iodide symporter (NIS), a member of the sodium/solute symporter family, actively transports iodide across the basolateral plasma membrane of the thyroid follicular cells.[supplied by OMIM]
    基因符号
    • -cotransporter)
    • SLC5A5
    • +I
    • NIS
    • Na
    • -symporter)
    UniProt编号
    • Q92911
    UniProt汇总 FUNCTION: SwissProt: Q92911 # Mediates iodide uptake in the thyroid gland.
    SIZE: 643 amino acids; 68666 Da
    SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors.
    DISEASE: SwissProt: Q92911 # Defects in SLC5A5 are the cause of iodide transport defect (ITD) [MIM:274400]. ITD is characterized by an inability of the thyroid to maintain a concentration difference of readily exchangeable iodine between the plasma and the thyroid gland. It is a cause of congenital hypothyroidism.
    SIMILARITY: SwissProt: Q92911 ## Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB3564,Anti-Sodium/Iodine Symporter Antibody, a.a. 625-643, clone FP5A

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