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描述 概述 Recombinant, human caspase-8 fused at the N- and C- termini to a His•Tag® sequence and expressed in E. coli as a single polypeptide. Subsequently undergoes spontaneous autoprocessing to yield the active enzyme. Suitable for the study of enzyme regulation and kinetics, target substrate cleavage, and inhibitor screening. MW: 11000 and 18000. M.W. 11,000 and 18,000 (heterodimer). 产品目录编号 218769 品牌系列 Calbiochem®
同义词 FLICE, MACH, Mch5 参考 参考 Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Boldin, M.P., et al. 1996. Cell 85, 803.
Fernandes-Alnemri, T., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 7464.
Muzio, M., et al. 1996. Cell 85, 817.产品信息 形式 Liquid 配方 In 100 mM NaCl, 50 mM HEPES, 10 mM DTT, 1 mM EDTA, 10% glycerol, 0.5% CHAPS, pH 7.4. 生物信息 纯度 ≥90% by SDS-PAGE 储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°).
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