merck millipore,默克密理愽
  • merck millipore,默克密理博,516483,Pepstatin A, Penetratin - Calbiochem

  • merck millipore,默克密理博,516483,Pepstatin A, Penetratin - Calbiochem

    产品名称：Pepstatin A, Penetratin - Calbiochem
    产品型号：516483
    A Pepstatin A that is ~75% less potent against Cathespins D/E than PepA in cell-free assays.

    merck millipore,默克密理博,516483,Pepstatin A, Penetratin - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,516483,Pepstatin A, Penetratin - Calbiochem

    重要规格表

    经验配方
    C₁₃₈H₂₂₉N₃₉O₂₈S
    描述
    概述 A Pepstatin A (PepA; Cat. No. 516481) penetratin (pAntp43-58) conjugate (PepA-P) that is ~75% less potent against Cathespins D/E (IC50 = 920 nM) than PepA in cell-free assays, presumably due to its decreased solubility. However, with its enhanced permeability, PepA-P is much more active than PepA in inhibiting cellular aspartic protease activity in MCF7 (94.1% vs. 54.6% inhibition wtih 10 µM respective compound), Boleths, and Dendritic cultures. PepA-P, but not PepA, effectively interferes with antigen processing by primary APCs and the subsequent activation of antigen-specific memory T cells.
    产品目录编号 516483
    品牌系列 Calbiochem®
    同义词 PepA-RQIKIWFQNRRMKWKK-OH, PepA-Antp₄₃₋₅₈
    参考
    参考 Zaidi, N., et al. 2007. Biochem. Biophys. Res. Commun. 364, 243.
    产品信息
    形式 White lyophilized solid
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₁₃₈H₂₂₉N₃₉O₂₈S
    化学配方 C₁₃₈H₂₂₉N₃₉O₂₈S
    Molar Mass 2914.6
    吸湿 Hygroscopic
    肽序列 PepA-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-CO₂H
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 H₂O
    肽序列 PepA-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-CO₂H
    安全信息
    S相 S: 22-24/25

    Do not breathe dust.
    Avoid contact with skin and eyes.
    储存和货运信息
    货运代码 Blue Ice Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,516483,Pepstatin A, Penetratin - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,MAB5414,Anti-Notch 1 Antibody, extracellular, clone 8G10
下一件merck millipore产品：merck millipore,默克密理博,ABS526,Anti-Perilipin-4, N-term Antibody


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