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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC513 描述 Anti-Rab11-FIP1/RCP Antibody Alternate Names - Rab-coupling protein
- Rab11 family-interacting protein 1
- Rab11-FIP1
背景信息 The protein Rab11-FIP1/RCP, or alternatively named Rab11 family-interacting protein 1, or Rab-coupling protein, and encoded by the human gene RAB11FIP1/RCP is an effector protein that interacts with Rab11 in the processes surrounding endosomal recycling. Rab11-FIP1/RCP also is involved in membrane trafficking in phagocytosis, as well as during axon growth, mediating integrin trafficking in various cancers. RAB11-FIP1/RCP has isoforms. Isoform 1 is non-membrane bound and is localized in the endosome and is involved in endosome recycling. Isoform 2 is more cytoplasmic being confined, for example, to the cytoplasmic phagosome vesicles and the phagosome membrane. Rab11-FIP1/RCP is expressed in multiple tissues and comprises one member of a large family of Rab11 family interacting proteins (Fab11-FIPs) that define discrete subdomains and carry out temporally distinct roles within the recycling and membrane trafficking system of the cell. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide. 应用 应用 This Anti-Rab11-FIP1/RCP Antibody is validated for use in western blotting, ICC & IP for the detection of Rab11-FIP1/RCP. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Rab11-FIP1/RCP in 10 µg of C2C12, HEK293, HeLa, HepG2, HUVEC, Jurkat, L6, NIH/3T3, PC-12, PC-3, RAW264.7 cell lysate.
Western Blotting Analysis: A representative lot from an independent laboratory detected Rab11-FIP1/RCP in Tac-TGN38 expressing HeLa cell lysates (Jing, J., et al. (2010). Mol Cell Biol. 21(17):3041-3053.).
Immunocytochemistry Analysis: A representative lot from an independent laboratory detected Rab11-FIP1/RCP in Tac-TGN38 expressing HeLa cells (Jing, J., et al. (2010). Mol Cell Biol. 21(17):3041-3053.).
Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated Rab11-FIP1/RCP from HeLa cell lysate (Jing, J., et al. (2010). Mol Cell Biol. 21(17):3041-3053.).生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human Rab11-FIP1/RCP. 宿主 Rabbit 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001002814
基因符号 - RCP
- RAB11FIP1
纯化方法 Affinity purified UniProt编号 - Q6WKZ4
产品使用声明 质量保证 Evaluated by Western Blotting in A431 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Rab11-FIP1/RCP in 10 µg of A431 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
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