merck millipore,默克密理愽
  • merck millipore,默克密理博,MABT188,Anti-Dynamin-1/2 Antibody, clone Hudy-1

  • merck millipore,默克密理博,MABT188,Anti-Dynamin-1/2 Antibody, clone Hudy-1

    产品名称：Anti-Dynamin-1/2 Antibody, clone Hudy-1
    产品型号：MABT188
    Anti-Dynamin-1/2 Antibody, clone Hudy-1 detects level of Dynamin-1/2 & has been published & validated for use in Western Blotting, Immunofluorescence.

    merck millipore,默克密理博,MABT188,Anti-Dynamin-1/2 Antibody, clone Hudy-1

  • 产品介绍
  • merck millipore,默克密理博,MABT188,Anti-Dynamin-1/2 Antibody, clone Hudy-1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    H, RWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABT188
    描述 Anti-Dynamin-1/2 Antibody, clone Hudy-1
    Alternate Names
    • Dynamin-1/2
    • Dynamin
    • Dynamin-1
    背景信息 Dynamin-1 & Dynamin-2 belong to the dynamin superfamily of large GTPases. Dynamins are multidomain proteins consisting of a GTP-binding domain, a middle domain, and a GTP-effector domain. Dynamins also contain a pleckstrin homology (PH) domain which may facilitate membrane binding. Dynamin-1 is highly abundant in the brain particularly at synaptic contacts, whereas Dynamin-2 is ubiquitously expressed in non-neuronal cells. Dynamins are involved in receptor-mediated endocytosis of clathrin-coated vesicles. Dynamin-1 interacts with an array of cellular targets via its SH3 binding domain and is implicated in late stages of vesicle formation by forming oligomers around the “neck” of budding vesicles and inducing membrane fission; it may also play a role in cytoskeleton rearrangement and cytoskinesis. Dynamin-2 is involved in the formation of clathrin-coated vesicles but may also be involved in the recycling of receptors between endosomes and the trans-Golgi network.
    产品信息
    格式 Purified
    控制
    • Rat brain tissue lysate
    演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4) and 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-Dynamin-1/2 Antibody, clone Hudy-1 detects level of Dynamin-1/2 & has been published & validated for use in Western Blotting, Immunofluorescence.
    主要应用
    • Western Blotting
    应用说明 Immunofluorescence Analysis: A representative lot was used by an independent laboratory in HeLa cells (Nicoziani, P., et al. (1999). Molecular Biology of the Cell. 11:481–495.)
    生物信息
    免疫原品种 Recombinant full length human Dynamin-1 expressed in transfected Sf9 cells.
    克隆 Hudy-1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 This antibody detects both Dynamin-1 and Dynamin-2. (Nicoziani, P., et al. (1999). Molecular Biology of the Cell. 11:481–495.)
    同种型 IgG1κ
    品种反应性 HumanRat
    Species Reactivity Note Demonstrated to react with Rat and Human.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001005336
    Entrez基因汇总 This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
    基因符号
    • DNM
    • DNM1
    纯化方法 Protein G purified
    UniProt编号
    • Q05193
    UniProt汇总 FUNCTION: Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.

    CATALYTIC ACTIVITY: GTP + H2O = GDP + phosphate.

    SUBUNIT STRUCTURE: Interacts with CAV1 and SH3GLB1. Binds SH3GL1, SH3GL2 and SH3GL3 (By similarity). Interacts with PHOCN By similarity. Interacts with SNX9.

    SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm › cytoskeleton. Note: Microtubule-associated.

    SEQUENCE SIMILARITIES: Belongs to the dynamin family.

    Contains 1 GED domain.

    Contains 1 PH domain.
    产品使用声明
    质量保证 Evaluated by Western Blot in rat brain tissue lysate.

    Western Blot Analysis: 0.5 µg/mL of this antibody detected Dynamin-1/2 on 10 µg of rat brain tissue lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABT188,Anti-Dynamin-1/2 Antibody, clone Hudy-1

上一件merck millipore产品：merck millipore,默克密理博,ABC513,Anti-Rab11-FIP1/RCP Antibody
下一件merck millipore产品：merck millipore,默克密理博,AG970-1MG,β Amyloid 1-42, aβ, ultra pure, NaOH, recombinant human


相关产品

merck millipore,默克密理博,ABC420,Anti-CYP27A1 Antibody merck millipore,默克密理博,ABC420,Anti-CYP27A1 Antibody

merck millipore,默克密理博,SF-151,EGFR; Human, Cyanine 5, RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-151,EGFR; Human, Cyanine 5, RNA Detection Probe,SmartFlare

merck millipore,默克密理博,PC255L,Anti-Parvalbumin Rabbit pAb merck millipore,默克密理博,PC255L,Anti-Parvalbumin Rabbit pAb

merck millipore,默克密理博,07-818,Anti-phospho-EGFR (Tyr1086) Antibody merck millipore,默克密理博,07-818,Anti-phospho-EGFR (Tyr1086) Antibody

merck millipore,默克密理博,ABC513,Anti-Rab11-FIP1/RCP Antibody merck millipore,默克密理博,ABC513,Anti-Rab11-FIP1/RCP Antibody

merck millipore,默克密理博,AG970-1MG,β Amyloid 1-42, aβ, ultra pure, NaOH, recombinant human merck millipore,默克密理博,AG970-1MG,β Amyloid 1-42, aβ, ultra pure, NaOH, recombinant human

merck millipore,默克密理博,400015,Caspase-1 Inhibitor IV - CAS 154674-81-4 - Calbiochem merck millipore,默克密理博,400015,Caspase-1 Inhibitor IV - CAS 154674-81-4 - Calbiochem

merck millipore,默克密理博,MAB5414,Anti-Notch 1 Antibody, extracellular, clone 8G10 merck millipore,默克密理博,MAB5414,Anti-Notch 1 Antibody, extracellular, clone 8G10

merck millipore,默克密理博,516483,Pepstatin A, Penetratin - Calbiochem merck millipore,默克密理博,516483,Pepstatin A, Penetratin - Calbiochem

merck millipore,默克密理博,ABS526,Anti-Perilipin-4, N-term Antibody merck millipore,默克密理博,ABS526,Anti-Perilipin-4, N-term Antibody


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部