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merck millipore,默克密理博,ABE327,Anti-Histone H2A Antibody
产品名称：Anti-Histone H2A Antibody
产品型号：ABE327
Use Anti-Histone H2A Antibody (Rabbit Polyclonal Antibody) validated in WB, IHC to detect Histone H2A also known as Histone H2A type 1, H2A.1, Histone H2A/p.
merck millipore,默克密理博,ABE327,Anti-Histone H2A Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE327 描述 Anti-Histone H2A Antibody Alternate Names - Histone H2A/p
- Histone H2A type 1
- H2A.1
背景信息 Histone H2A is one of four components of the core nucleosomal structure. The nucleosome represents a unit of chromatin in which DNA is wrapped around a histone octamer. Histones undergo a number of post-translational modifications (PTM) in response to various stimuli that may induce changes in the structure of the nucleosome and hide or expose DNA sequences. Histone H2A, in particular, undergoes acetylation on lysine 5 by the Tip60 enzyme which may promote unfolding of chromatin and transcription. In addition, H2A is phosphorylated on serine 1 and serine 139 (H2A.X) residues which mark mitosis and gene repression, and DNA damage, respectively. Gene repression may also result from the sumoylation of H2A’s lysine 126 residue. In addition, ubiquitination of the H2A lysine 119 residue may play a role in spermatogenesis. It is the pattern of different modifications on several histone residues that alter chromatin, rather than modification of single residues. 产品信息 格式 Affinity Purified 控制 - HeLa acid extract and recombinant histone proteins
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Use Anti-Histone H2A Antibody (Rabbit Polyclonal Antibody) validated in WB, IHC to detect Histone H2A also known as Histone H2A type 1, H2A.1, Histone H2A/p. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistchemistry Analysis: A 1:1,000 dilution from a representative lot detected Histone H2A in liver and kidney tissues. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the C-terminus of human Histone H2A. 表位 C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes Histone H2A at the C-terminus. 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with Human, Mouse, and Rat. Broad species reactivity expected based on sequence similarity. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_003500
基因符号 - H2AFN
- HIST1H2AG
- H2AFP
- HIST1H2AI
- H2AFC
- HIST1H2AK
- H2AFD
- HIST1H2AL
- H2AFI
- HIST1H2AM
纯化方法 Affinity purified UniProt编号 - P0C0S8
产品使用声明 质量保证 Evaluated by Western Blot in HeLa acid extract and recombinant histone proteins.
Western Blot Analysis: 0.1 µg/mL of this antibody detected Histone H2A on 10 µg of HeLa acid extract and recombinant histone proteins.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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