merck millipore,默克密理愽
  • merck millipore,默克密理博,GF174,Sonic HedgeHog (Shh) Protein, Human Recombinant

  • merck millipore,默克密理博,GF174,Sonic HedgeHog (Shh) Protein, Human Recombinant

    产品名称：Sonic HedgeHog (Shh) Protein, Human Recombinant
    产品型号：GF174
    The hedgehog (hh) gene encoding a secreted protein was originally identified in Drosophila as a segment polarity gene.

    merck millipore,默克密理博,GF174,Sonic HedgeHog (Shh) Protein, Human Recombinant

  • 产品介绍
  • merck millipore,默克密理博,GF174,Sonic HedgeHog (Shh) Protein, Human Recombinant

    重要规格表

    来源 纯度
    E. coli.Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
    描述
    产品目录编号 GF174
    描述 Sonic HedgeHog (Shh) Protein, Human Recombinant
    Alternate Names
    • HHG-1
    • SHH
    背景信息 The hedgehog (hh) gene encoding a secreted protein was originally identified in Drosophila as a segment polarity gene. The vertebrate homologues of hh comprise several proteins including sonic hedgehog (Shh), Indian hedgehog (Ihh), and Desert hedgehog (Dhh). Hedgehog proteins are important signaling molecules during embryonic development. Shh is expressed in key embryonic tissues such as the Hensen’s node, the zone of polarizing activity in the posterior limb bud, the notochord, and the floor plate of the neural tube. Shh is involved in regulating the patterning of the developing central nervous system, somite, and limb. Shh plays an important role in the development of particular tissues such as whisker, hair, foregut, tooth and bone. Evidence also suggests that Shh is involved in regulating stem cell fates of neural and hematopoietic lineages, and that aberrant Shh signaling is implicated in basal cell carcinomas and other diseases. Shh genes are highly conserved and have been identified in a variety of species including human, mouse, frog, fish, and chicken. Recombinant E. coli derived Human Sonic HedgeHog is a 20.0 kDa protein consisting of 176 amino acid residues, including an N-terminal Ile-Val-Ile sequence substituted for the natural occurring chemically modified Cys residue.
    产品信息
    演示 Product is filtered through a 0.2 micron filter before lyophilization.
    应用
    应用 The hedgehog (hh) gene encoding a secreted protein was originally identified in Drosophila as a segment polarity gene.
    生物信息
    纯度 Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
    来源 E. coli.
    交叉反应性 None
    UniProt编号
    • Q15465
    产品使用声明
    质量保证 Bioactivity assay: Determined by its ability to induce alkaline phosphatase production by C3H/10T1/2 (CCL-226) cells. The expected ED50 for this effect is 0.8-1.0 μg/ml.
    储存和货运信息
    存储条件 Store at -20°C for up to 6 months from date of receipt.
    包装信息
    数量 25 µg

    merck millipore,默克密理博,GF174,Sonic HedgeHog (Shh) Protein, Human Recombinant

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