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merck millipore,默克密理博,FCMAB257P,Milli-Mark™Anti-Glial Fibrillary Acidic Protein-PE Antibody, clone GA5
产品名称：Milli-Mark™Anti-Glial Fibrillary Acidic Protein-PE Antibody, clone GA5
产品型号：FCMAB257P
Milli-MarkAnti-Glial Fibrillary Acidic Protein-PE Antibody, clone GA5 detects level of Glial Fibrillary Acidic Protein & has been published & validated for use in FC.
merck millipore,默克密理博,FCMAB257P,Milli-Mark™Anti-Glial Fibrillary Acidic Protein-PE Antibody, clone GA5
- 产品介绍
- merck millipore,默克密理博,FCMAB257P,Milli-Mark™Anti-Glial Fibrillary Acidic Protein-PE Antibody, clone GA5
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC M Phycoerythrin Monoclonal Antibody 描述 产品目录编号 FCMAB257P 商名 - Milli-Mark
描述 Milli-Mark™Anti-Glial Fibrillary Acidic Protein-PE Antibody, clone GA5 Alternate Names - GFAP
背景信息 Glial fibrillary acidic protein is a class-III intermediate filament. GFAP is the main constituent of intermediate filaments in astrocytes and serves as a cell specific marker that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system. 产品信息 格式 Phycoerythrin 控制 - U251 cells
演示 Purified mouse monoclonal IgG1 conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA. 应用 应用 Milli-MarkAnti-Glial Fibrillary Acidic Protein-PE Antibody, clone GA5 detects level of Glial Fibrillary Acidic Protein & has been published & validated for use in FC. 主要应用 - Flow Cytometry
生物信息 免疫原品种 Purified glial filament (Debus, E., 1983). 克隆 GA5 宿主 Mouse 特异性 Antibody recognizes Human Glial Fibrillary Acidic Protein. 同种型 IgG1κ 品种反应性 Human Species Reactivity Note Tested and passed on Human. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_002046
Entrez基因汇总 This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant has been described, but its full length sequence has not been determined 基因符号 - FLJ45472
- GFAP
纯化方法 Protein A Purified UniProt编号 - P14136
UniProt汇总 FUNCTION: SwissProt: P14136 # GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
SIZE: 432 amino acids; 49880 Da
SUBUNIT: Isoform 3 interacts with N-terminus of PSEN1.
SUBCELLULAR LOCATION: Cytoplasm. Note=Associated with intermediate filaments.
DISEASE: SwissProt: P14136 # Defects in GFAP are a cause of Alexander disease [MIM:203450]. Alexander disease is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes. The most common form affects infants and young children, and is characterized by progressive failure of central myelination, usually leading to death usually within the first decade. Infants with Alexander disease develop a leukoencephalopathy with macrocephaly, seizures, and psychomotor retardation. Patients with juvenile or adult forms typically experience ataxia, bulbar signs and spasticity, and a more slowly progressive course.
SIMILARITY: SwissProt: P14136 ## Belongs to the intermediate filament family. ...产品使用声明 质量保证 Evaluated by flow cytometry using U251 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt. 包装信息 数量 100 tests
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