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merck millipore,默克密理博,ABS477,Anti-LBP Antibody
产品名称:Anti-LBP Antibody
产品型号:ABS477
Anti-LBP Antibody is a highly specific rabbit polyclonal antibody, that targets Lipopolysaccharide binding protein & has been tested in western blotting, IHC & Immunofluorescence.
merck millipore,默克密理博,ABS477,Anti-LBP Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H, M IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS477 描述 Anti-LBP Antibody Alternate Names - LBP
- Lipopolysaccharide-binding protein
背景信息 Lipopolysaccharide binding protein (LBP) is a secreted protein produced by hepatocytes, immune cells and epithelial cells that binds lipid A protein on bacterial lipopolysaccharides (LPS) present on the outer membranes of all gram negative bacteria. When bound to LPS, LBP potentiates the affinity of LPS for CD14 and likely plays a role in regulating LPS-dependent monocyte responses. LBP also interacts with the innate immunity receptors TLR2 and TLR4 and the co-receptor MD-2 and thus plays a key role in our innate response to bacterial infection. Because LBP expression is induced upon bacterial infection it is being studied as a possible biomarker for infection, particularly in difficult cases such as acute appendicitis, sepsis, infectious endocarditis, periodontal disease, febrile urinary infections and even cardiovascular disease. EMD-Millipore’s Anti-LBP rabbit polyclonal antibody has been tested in western blot on mouse liver lysates and in paraffin embedded immunohistochemistry on human liver cancer tissue sections and in immunofluorescent immunocytochemistry on HepG2 cell in culture. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Anti-LBP Antibody is a highly specific rabbit polyclonal antibody, that targets Lipopolysaccharide binding protein & has been tested in western blotting, IHC & Immunofluorescence. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected LBP in human liver cancer tissue.
Immunofluorescence Analysis: A 1:25 dilution from a representative lot detected LBP in HepG2 cells.生物信息 免疫原品种 GST-tagged fusion protein corresponding to human LBP. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 HumanMouse 抗体类型 Polyclonal Antibody 基因符号 - LBP
纯化方法 Antigen Affinity purified UniProt编号 - P18428
产品使用声明 质量保证 Evaluated by Western Blotting in Mouse liver tissue lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected LBP in Mouse liver tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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