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  • merck millipore,默克密理博,ABT282,Anti-phospho-NUMA1 Antibody (Thr2055)

  • merck millipore,默克密理博,ABT282,Anti-phospho-NUMA1 Antibody (Thr2055)

    产品名称：Anti-phospho-NUMA1 Antibody (Thr2055)
    产品型号：ABT282
    This Anti-phospho-NUMA1 Antibody (Thr2055) is validated for use in Western Blotting and Peptide Inhibition Assay for the detection of phospho-NUMA1 (Thr2055).

    merck millipore,默克密理博,ABT282,Anti-phospho-NUMA1 Antibody (Thr2055)

  • 产品介绍
  • merck millipore,默克密理博,ABT282,Anti-phospho-NUMA1 Antibody (Thr2055)

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 ABT282
    描述 Anti-phospho-NUMA1 Antibody (Thr2055)
    Alternate Names
    • SP-H antigen
    • Nuclear mitotic apparatus protein 1
    • NuMA protein
    背景信息 NUMA1 or NUMA protein is an interesting and major component of the nuclear matrix of eukaryotic cells. NUMA1 is a highly abundant protein component that appears to serve a non-structural role but is needed for mitotic spindle poles and centrosome formation as well as a linker of microtubules. These functions are important for proper cytokinesis and the setup of the proper polarity axis during cell division. NUMA1 resides in the nuclear matrix during interphase. NUMA1 dissociates from condensing chromosomes during early prophase, and relocates to the spindle poles via a dynein/dynamin complex, and it remains there until the anaphase onset. Thus NUMA1 then can be found in the nucleus during cell rest and cytoplasmically and centrosome localized during cytokinesis. NUMA1 phosphorylation occurs by CDK1 and phosphorylation increases solubility and promotes association with dynein and subsequent translocation to the spindle poles.
    产品信息
    格式 Affinity Purified
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 This Anti-phospho-NUMA1 Antibody (Thr2055) is validated for use in Western Blotting and Peptide Inhibition Assay for the detection of phospho-NUMA1 (Thr2055).
    主要应用
    • Western Blotting
    应用说明 Peptide Inhibition Analysis: A 1:500 dilution from a representative lot blocked NUMA1 phosphorylated at Thr2055 in Hydroxyurea treated HeLa nuclear extract.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to the tail region of human NUMA1 phosphorylated at Thr2055.
    表位 Tail Region
    浓缩 Please refer to lot specific datasheet.
    宿主 Rabbit
    品种反应性 Human
    Species Reactivity Note Human. Predicted to react with Mouse, Rat, Bovine based on 100% sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_006176
    基因符号
    • NUMA
    • NUMA1
    修改
    • Phosphorylation
    纯化方法 Affinity purified
    UniProt编号
    • Q14980
    产品使用声明
    质量保证 Evaluated by Western Blotting in HeLa nuclear extract and Hydroxyurea treated HeLa nuclear extract.

    Western Blotting Analysis: A 1:500 dilution of this antibody detected NUMA1 phosphorylated at Thr2055 in 10 µg of HeLa nuclear extract and Hydroxyurea treated HeLa nuclear extract.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,ABT282,Anti-phospho-NUMA1 Antibody (Thr2055)

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下一件merck millipore产品：merck millipore,默克密理博,BH-MED,Bioptechs Objective Heater-Medium (150819-13)


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