merck millipore,默克密理愽
  • merck millipore,默克密理博,236015,COX-2 Inhibitor V, FK3311 - CAS 116686-15-8 - Calbiochem

  • merck millipore,默克密理博,236015,COX-2 Inhibitor V, FK3311 - CAS 116686-15-8 - Calbiochem

    产品名称：COX-2 Inhibitor V, FK3311 - CAS 116686-15-8 - Calbiochem
    产品型号：236015
    The COX-2 Inhibitor V, FK3311, also referenced under CAS 116686-15-8, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications.

    merck millipore,默克密理博,236015,COX-2 Inhibitor V, FK3311 - CAS 116686-15-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,236015,COX-2 Inhibitor V, FK3311 - CAS 116686-15-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₅H₁₃F₂NO₄S116686-15-8
    描述
    概述 A cell-permeable and orally available sulfonanilide that acts as a COX-2-selective non-steroidal anti-inflammatory drug (NSAID). Shown to exhibit 500-fold greater potency in inhibiting the LPS-induced (IC50 = 316 nM in human mononuclear cells) than the non-induced/constitutive (IC50 = 160 µM in human platelets) TxB2 production in vitro and effectively alleviate warm ischemia-reperfusion injury in the canine liver and rat lung in vivo.
    产品目录编号 236015
    品牌系列 Calbiochem®
    同义词 4ʹ-Acetyl-2ʹ-(2,4-Difluorophenoxy)methanesulfonanilide
    参考
    参考 Otani, Y., et al. 2007. J. Invest. Surg. 20, 175.
    Sunose, Y., et al. 2001. Transplant Proc. 33, 862.
    Grossman, C.J., et al. 1995. Inflamm. Res. 44, 253.
    Nakamura, K., et al. 1993. Chem. Pharm. Bull. 41, 2050.
    Tsuji, K., et al. 1992. Chem. Pharm. Bull. 40, 2399.
    产品信息
    CAS号 116686-15-8
    形式 White solid
    Hill配方 C₁₅H₁₃F₂NO₄S
    化学配方 C₁₅H₁₃F₂NO₄S
    Molar Mass 341.3
    结构配方图像
    生物信息
    纯度 ≥98% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    安全信息
    S相 S: 22-24/25-36/39

    Do not breathe dust.
    Avoid contact with skin and eyes.
    Wear suitable protective clothing and eye/face protection.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,236015,COX-2 Inhibitor V, FK3311 - CAS 116686-15-8 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,FCMAB257P,Milli-Mark™Anti-Glial Fibrillary Acidic Protein-PE Antibody, clone GA5
下一件merck millipore产品：merck millipore,默克密理博,203734,Brevetoxin PbTx-3, Ptychodiscus brevis - CAS 85079-48-7 - Calbiochem


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