merck millipore,默克密理愽
  • merck millipore,默克密理博,14-860,UbcH5a Protein, recombinant, 100 µg

  • merck millipore,默克密理博,14-860,UbcH5a Protein, recombinant, 100 µg

    产品名称：UbcH5a Protein, recombinant, 100 µg
    产品型号：14-860
    Recombinant fusion protein containing human UbcH5a with an N-terminal His-tag. For use in Activity Assays.

    merck millipore,默克密理博,14-860,UbcH5a Protein, recombinant, 100 µg

  • 产品介绍
  • merck millipore,默克密理博,14-860,UbcH5a Protein, recombinant, 100 µg

    重要规格表

    主要应用 Entrez基因编号 品种 Uni Prot编号
    ACTNM_003338.3HumanP51668
    描述
    产品目录编号 14-860
    品牌系列 Upstate
    商名
    • Upstate
    描述 UbcH5a Protein, recombinant, 100 µg
    概述 Recombinant fusion protein containing human UbcH5a with an N-terminal His-tag.
    产品信息
    演示 100 µg UbcH5a recombinant in 100 µL of 50mM Tris-HCl, pH 7.5, 270mM Sucrose, 150mM NaCl, 0.1 mMEGTA, 0.1% 2-mercaptoethanol, 0.02% Brij-35, 0.2mM PMSF, and 1mM Benzamidine. Frozen solution.
    应用
    应用 Recombinant fusion protein containing human UbcH5a with an N-terminal His-tag. For use in Activity Assays.
    主要应用
    • Activity Assay
    生物信息
    浓缩 1 mg/ml
    纯度 ~90% by SDS PAGE and Coomassie blue staining.
    来源 Expressed in E. coli
    品种 Human
    Entrez基因编号
    • NM_003338.3
    Entrez基因汇总 The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
    基因符号
    • UbcH5
    • UBE2D1
    • UBCH5
    • UBCH5A
    • UbcH5A
    • SFT
    • E2
    • UBC4/5
    • E2(17)KB1
    纯化方法 ProBond Resin chromatography
    UniProt编号
    • P51668
    UniProt汇总 FUNCTION: SwissProt: P51668 # Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53.
    SIZE: 147 amino acids; 16602 Da
    SUBUNIT: Component of a E3 ubiquitin ligase complex containing UBE2D1, SIAH1, CACYBP/SIP, SKP1A, APC and TBL1X.
    SIMILARITY: SwissProt: P51668 ## Belongs to the ubiquitin-conjugating enzyme family.
    产品使用声明
    质量保证 Routinely evaluated by ubiquitin assay
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 2 years at -70°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,14-860,UbcH5a Protein, recombinant, 100 µg

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下一件merck millipore产品：merck millipore,默克密理博,FCMAB257P,Milli-Mark™Anti-Glial Fibrillary Acidic Protein-PE Antibody, clone GA5


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