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merck millipore,默克密理博,FCMAB215P,Milli-Mark™ Anti-CD138-PE Antibody, clone MI15
产品名称:Milli-Mark™ Anti-CD138-PE Antibody, clone MI15
产品型号:FCMAB215P
Detect CD138 using this Milli-Mark Anti-CD138-PE Antibody, clone MI15 validated for use in FC.
merck millipore,默克密理博,FCMAB215P,Milli-Mark™ Anti-CD138-PE Antibody, clone MI15
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC M Phycoerythrin Monoclonal Antibody 描述 产品目录编号 FCMAB215P 商名 - Milli-Mark
描述 Milli-Mark™ Anti-CD138-PE Antibody, clone MI15 Alternate Names - SYND1
- Syndecan-1
背景信息 CD138 is a transmembrane proteoglycan, bearing heparin sulphates and sometimes chondriotin sulfates. It consists of a 30.5 kDa core protein with 5 putative glycosaminoglycans attachment sites. CD138 is a member of the syndecan family. The reported Mr of CD138 ranges from 85,000 to 92,000, presumably depending on the glycosaminoglycan pattern of the molecule (Wijdenes, 1997). Within the hematopoietic system, CD138 is mainly confined to late stages of B-cell differentiation. It is typically expressed at high cellular density in plasma cells (Gattei, 1999). In mature tissues, CD138 is expressed by simple and stratified epithelia, fibroblasts, stratified keratinocytes and endothelial cells (Wijdenes, 1997). Anti-CD138, MI15, was included in the Sixth International Workshop and Conference on Human Leucocytes Differentiation Antigens, and studies by a number of different laboratories confirmed its reactivity with CD138 (Wijdenes, 1997). 产品信息 格式 Phycoerythrin 控制 - U266 cells
演示 Purified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2. 应用 应用 Detect CD138 using this Milli-Mark Anti-CD138-PE Antibody, clone MI15 validated for use in FC. 主要应用 - Flow Cytometry
生物信息 免疫原品种 A mixture of U266 and XG-1 human myeloma cell lines 克隆 MI15 宿主 Mouse 特异性 Antibody recognizes Human CD138 antigen 同种型 IgG1κ 品种反应性 Human Species Reactivity Note Tested and passed on Human. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001006947
Entrez基因汇总 The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. 纯化方法 Protein A Purified UniProt编号 - P18827
UniProt汇总 Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. 产品使用声明 质量保证 Evaluated by flow cytometry using U266 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt. 包装信息 数量 100 tests
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