merck millipore,默克密理愽
  • merck millipore,默克密理博,475944,Myeloperoxidase Inhibitor-I - CAS 5351-17-7 - Calbiochem

  • merck millipore,默克密理博,475944,Myeloperoxidase Inhibitor-I - CAS 5351-17-7 - Calbiochem

    产品名称：Myeloperoxidase Inhibitor-I - CAS 5351-17-7 - Calbiochem
    产品型号：475944
    The Myeloperoxidase Inhibitor-I, also referenced under CAS 5351-17-7, controls the biological activity of Myeloperoxidase. This small molecule/inhibitor is primarily used for Inflammation/Immunology a More>>

    merck millipore,默克密理博,475944,Myeloperoxidase Inhibitor-I - CAS 5351-17-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,475944,Myeloperoxidase Inhibitor-I - CAS 5351-17-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₇H₉N₃O5351-17-7
    描述
    概述 A benzoic acid hydrazide analog that acts as a potent, irreversible, and specific inhibitor of the peroxidation activity of myeloperoxidase (MPO; IC50 = 300 nM). Does not inhibit catalase or glutathione peroxidase activities. Does not affect the production of superoxide by neutrophils. Shown to inhibit H2O2-induced apoptosis in HL-60, human leukemia cells.
    产品目录编号 475944
    品牌系列 Calbiochem®
    参考
    参考 Engelmann, I., et al. 2000. Redox Report 5, 207.
    Wagner, B.A., et al. 2000. J. Biol. Chem. 275, 22461.
    Burner, U., et al. 1999. J. Biol. Chem. 274, 9494.
    Kettle, A.J., et al. 1997. Biochem. J. 321, 503.
    Kettle, A.J., et al. 1995. Biochem. J. 308, 559.
    产品信息
    CAS号 5351-17-7
    具有ATP竞争性 N
    形式 Beige solid
    Hill配方 C₇H₉N₃O
    化学配方 C₇H₉N₃O
    Molar Mass 151.2
    可逆 N
    结构配方图像
    生物信息
    主靶 Myeloperoxidase
    主靶IC50 300 nM against myeloperoxidase (MPO)
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO or Dilute Acids
    GHS安全信息
    RTECS DG2580000
    安全信息
    R相 R: 36/37/38

    Irritating to eyes, respiratory system and skin.
    S相 S: 26-36

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,475944,Myeloperoxidase Inhibitor-I - CAS 5351-17-7 - Calbiochem

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