• merck millipore,默克密理博,EZRGRT-91K,Rat/Mouse Ghrelin (total) ELISA
  • merck millipore,默克密理博,EZRGRT-91K,Rat/Mouse Ghrelin (total) ELISA

    产品名称:Rat/Mouse Ghrelin (total) ELISA
    产品型号:EZRGRT-91K
    This Rat/Mouse Ghrelin (total) ELISA is used to measure & quantify Ghrelin (total) levels in Metabolism & Endocrine research.

    merck millipore,默克密理博,EZRGRT-91K,Rat/Mouse Ghrelin (total) ELISA

  • 产品介绍
  • merck millipore,默克密理博,EZRGRT-91K,Rat/Mouse Ghrelin (total) ELISA

    重要规格表

    可用的分析物 品种反应性 主要应用 检测方法
    Ghrelin (Total)M, RELISAColorimetric, Fluorescent
    描述
    产品目录编号 EZRGRT-91K
    描述 Rat/Mouse Ghrelin (total) ELISA
    背景信息 Circulating ghrelin is a multifunctional hormone secreted primarily by the stomach. Originally found as an endogenous ligand for the growth hormone secretagogue receptor, it is also an appetite-stimulating hormone in the regulation of energy homeostasis. It consists of 28 amino acids and the n-octanoylation of serine-3 position is necessary for its bioactivity. The acylated form is extremely unstable in the blood; consequently, the predominant form is des-octanoyl ghrelin. Long considered a key player in obesity, ghrelin may also play a role in maintaining the balance between insulin and glucose and the development of diabetes. The spike in insulin secretion occurring after eating usually correlates with a dip in ghrelin production. Researchers determined that in rat models of uncontrolled diabetes, food intake still suppressed ghrelin concentrations in the blood, but only approximately half as effectively as when insulin was present.
    产品信息
    检测方法 ColorimetricFluorescent
    精度(%)
    • Inter-assay: Serum: 1.8-4.5% Plasma: 2.0-3.2%
    • Intra-assay: Serum: 0.7–1.3% Plasma: 1.1–1.7%
    应用
    应用 This Rat/Mouse Ghrelin (total) ELISA is used to measure & quantify Ghrelin (total) levels in Metabolism & Endocrine research.
    主要应用
    • ELISA
    应用说明 Room temperature, 3 hour assay, 20 μL sample size (serum or plasma)
    生物信息
    特异性 Canine Ghrelin (Active) - 71%
    Human Ghrelin (Active) - 115%
    Human Des-Octanoyl Ghrelin - 249%
    Porcine Ghrelin (Active) - 48%
    Rat/Mouse Ghrelin (Active) - 85%
    Rat/Mouse Des-Octanoyl Ghrelin - 100%
    品种反应性 MouseRat
    可用的分析物
    • Ghrelin (Total)
    UniProt编号
    • Q9QYH7 (rat)
    • Q9UBU3
    • Q9EQX0 (mouse)
    准确度
    • Serum: (Active Ghrelin) 80-103%
    • Plasma: (Active Ghrelin) 86-102%
    • Plasma: (Des-octanoyl Ghrelin) 95-107%
    • Serum: (Des-octanoyl Ghrelin) 92-103%
    理化信息
    稀释的线性 Serum: 95.7–104.7% Plasma: 95–117%
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    包装信息
    数量 96-well strip plate

    merck millipore,默克密理博,EZRGRT-91K,Rat/Mouse Ghrelin (total) ELISA

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