merck millipore,默克密理愽
  • merck millipore,默克密理博,481984,Nifuroxazide - CAS 965-52-6 - Calbiochem

  • merck millipore,默克密理博,481984,Nifuroxazide - CAS 965-52-6 - Calbiochem

    产品名称：Nifuroxazide - CAS 965-52-6 - Calbiochem
    产品型号：481984
    A cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcription activity.

    merck millipore,默克密理博,481984,Nifuroxazide - CAS 965-52-6 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,481984,Nifuroxazide - CAS 965-52-6 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₂H₉N₃O₅965-52-6
    描述
    概述 A cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcription activity (IC50 = 3 µM against IL-6-induced STAT3 activation in U3A cells), while exhibiting little effect against TNF-α-induced NF-κB activation in 293 cells. Shown to inhibit cellular tyrosine phosphorylations of JAK2/TYK2/STAT3 (IC50 = 10 µM against tyr705 of STAT3 in U266 cells), but not those of Akt/EGFR/JAK1/MAPK/Src or the ser727 phosphorylation of STAT3.
    产品目录编号 481984
    品牌系列 Calbiochem®
    同义词 5-Nitro-2-furaldehyde-p-hydroxybenzoylhydrazone
    参考
    参考 Nelson, E.A., et al. 2008. Blood 112, 5095.
    产品信息
    CAS号 965-52-6
    形式 Bright yellow solid
    Hill配方 C₁₂H₉N₃O₅
    化学配方 C₁₂H₉N₃O₅
    Molar Mass 275.2
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,481984,Nifuroxazide - CAS 965-52-6 - Calbiochem

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