merck millipore,默克密理愽
  • merck millipore,默克密理博,MABT117,Anti-Endoglin (CD105) Antibody, clone 44G4

  • merck millipore,默克密理博,MABT117,Anti-Endoglin (CD105) Antibody, clone 44G4

    产品名称：Anti-Endoglin (CD105) Antibody, clone 44G4
    产品型号：MABT117
    Anti-Endoglin (CD105) Antibody, clone 44G4 is an antibody against Endoglin (CD105) for use in FC, IH & IP.

    merck millipore,默克密理博,MABT117,Anti-Endoglin (CD105) Antibody, clone 44G4

  • 产品介绍
  • merck millipore,默克密理博,MABT117,Anti-Endoglin (CD105) Antibody, clone 44G4

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, FCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABT117
    描述 Anti-Endoglin (CD105) Antibody, clone 44G4
    Alternate Names
    • CD104
    • Endoglin
    背景信息 Endoglin (CD105) is a homodimeric integral membrane glycoprotein comprised of a 95 kDa subunit. Endoglin is a component of the TGF-β receptor system that functions as an ancillary receptor influencing binding of the Transforming Growth Factor beta (TGF-β) family of ligands to signaling receptors. Endoglin binds to TGF-β1 and TGF-β3 with high affinity, but does not bind TGF-β2. Endoglin is expressed by vascular endothelial cells and syncytiotrophoblasts of placenta and is weakly expressed by stromalfibroblasts. Endoglin is also expressed by U937 cells and by activated macrophages. Endoglin expression is up-regulated on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation.
    产品信息
    格式 Purified
    控制
    • HUVEC cells
    演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-Endoglin (CD105) Antibody, clone 44G4 is an antibody against Endoglin (CD105) for use in FC, IH & IP.
    主要应用
    • Immunohistochemistry
    • Flow Cytometry
    应用说明 Immunohistochemistry Analysis: A representative lot was used by an independent laboratory to detect Endoglin in normal human lymph node, tonsil, spleen thrymus, liver, breast, lung, and kidney specimens (Gougos, A., and Letarte, M. (1988). J Immunol. 141(6):1925-1933).

    Immunoprecipitation Analysis: A representative lot was used by an independent laboratory to IP Endoglin from HOON, NALM-6, 3104, 3161, HL-60, U-937, EM-3 and KG-1a cells (Gougos, A., and Letarte, M. (1988). J Immunol. 141(6):1925-1933).
    生物信息
    免疫原品种 Whole HOON Pre-B Leukemic Cells
    克隆 44G4
    宿主 Mouse
    同种型 IgG1κ
    品种反应性 Human
    Species Reactivity Note Demonstrated to react with Human.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_000109
    Entrez基因汇总 Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex as it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    基因符号
    • END
    • ENG
    纯化方法 Protein G Purified
    UniProt编号
    • P17813
    UniProt汇总 FUNCTION: Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.

    SUBUNIT: Homodimer that forms an heteromeric complex with the signaling receptors for transforming growth factor-beta: TGF-beta receptors I and/or II. It is able to bind TGF-beta 1, and 3 efficiently and TGF-beta 2 less efficiently.

    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    产品使用声明
    质量保证 Evaluated by Flow Cytometry in HUVEC cells.

    Flow Cytometry Analysis: A 1:200 dilution of this antibody detected Endoglin in HUVEC cells.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MABT117,Anti-Endoglin (CD105) Antibody, clone 44G4

上一件merck millipore产品：merck millipore,默克密理博,69101,Carbenicillin
下一件merck millipore产品：merck millipore,默克密理博,MAB2174,Anti-Huntingtin Protein Antibody, a.a. 549-679, clone mHD549


相关产品

merck millipore,默克密理博,481984,Nifuroxazide - CAS 965-52-6 - Calbiochem merck millipore,默克密理博,481984,Nifuroxazide - CAS 965-52-6 - Calbiochem

merck millipore,默克密理博,MAB2247-I,Anti-Integrin β1 Antibody, clone 12G10 merck millipore,默克密理博,MAB2247-I,Anti-Integrin β1 Antibody, clone 12G10

merck millipore,默克密理博,HSTCMAG28SPMX21,MILLIPLEX MAP Human High Sensitivity T Cell Panel Premixed 21-plex - Immunology Multiplex Assay merck millipore,默克密理博,HSTCMAG28SPMX21,MILLIPLEX MAP Human High Sensitivity T Cell Panel Premixed 21-ple...

merck millipore,默克密理博,324629,Eg5 Inhibitor VI - Calbiochem merck millipore,默克密理博,324629,Eg5 Inhibitor VI - Calbiochem

merck millipore,默克密理博,69101,Carbenicillin merck millipore,默克密理博,69101,Carbenicillin

merck millipore,默克密理博,MAB2174,Anti-Huntingtin Protein Antibody, a.a. 549-679, clone mHD549 merck millipore,默克密理博,MAB2174,Anti-Huntingtin Protein Antibody, a.a. 549-679, clone mHD549

merck millipore,默克密理博,MABE152,Anti-SRp55 Antibody, clone 9-1-56 merck millipore,默克密理博,MABE152,Anti-SRp55 Antibody, clone 9-1-56

merck millipore,默克密理博,407293,α-Interferon, Mouse, Recombinant, E. coli merck millipore,默克密理博,407293,α-Interferon, Mouse, Recombinant, E. coli

merck millipore,默克密理博,ABF233,Anti-IRF5 Antibody merck millipore,默克密理博,ABF233,Anti-IRF5 Antibody

merck millipore,默克密理博,70912,MagPrep Silica Particles merck millipore,默克密理博,70912,MagPrep Silica Particles


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部