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merck millipore,默克密理博,MAB2247-I,Anti-Integrin β1 Antibody, clone 12G10
产品名称:Anti-Integrin β1 Antibody, clone 12G10
产品型号:MAB2247-I
This Anti-Integrin β1 Antibody, clone 12G10 is validated for use in Western Blotting, Flow Cytometry, Immunofluorescence for the detection of Integrin β1.
merck millipore,默克密理博,MAB2247-I,Anti-Integrin β1 Antibody, clone 12G10
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MAB2247-I Replaces MAB2247 描述 Anti-Integrin β1 Antibody, clone 12G10 Alternate Names - CD29
- Integrin beta-1
- Fibronectin receptor subunit beta
- VLA-4 subunit beta
背景信息 Integrin beta 1, also known as CD29, is a 130 kDa transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits (including alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, and alpha 6, also known as CD49a, CD49b, CD49c, CD49d, CD49e, and CD49f, respectively) to form the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis, and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. Interactions between integrins and the extracellular matrix lead to activation of signal transduction pathways and regulation of gene expression. 产品信息 格式 Purified 控制 - HeLa cells
演示 Purified mouse monoclonal IgG1κ in PBS containing 0.1% sodium azide. 应用 应用 This Anti-Integrin β1 Antibody, clone 12G10 is validated for use in Western Blotting, Flow Cytometry, Immunofluorescence for the detection of Integrin β1. 主要应用 - Flow Cytometry
- Western Blotting
应用说明 Western Blot Analysis: 0.5 µg/mL from a representative lot detected Integrin β1 in 10 µg of Integrin purified protein.
Immunofluorescence Analysis: A representative lot was used in an independent laboratory in mouse lung tissue. (Chen P., et al. (2009). PLoS ONE. 4(8):e6565.)生物信息 免疫原品种 Purified human β1 Integrin preparation from HT1080 fibrosarcoma cell extract 克隆 12G10 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_002283
基因符号 - MSK12
- ITGB1
- FNRB
- MDF2
纯化方法 Protein G purified UniProt编号 - P05556
产品使用声明 质量保证 Evaluated by Flow Cytometry in HeLa cells.
Flow Cytometry Analysis: 1 µg of this antibody detected Integrin β1 in HeLa cells.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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