merck millipore,默克密理博,HSTCMAG28SPMX21,MILLIPLEX MAP Human High Sensitivity T Cell Panel Premixed 21-plex

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merck millipore,默克密理博,HSTCMAG28SPMX21,MILLIPLEX MAP Human High Sensitivity T Cell Panel Premixed 21-plex - Immunology Multiplex Assay

可用的分析物	品种反应性	主要应用	检测方法
IL-17A, IL-21, IL-23, ITAC, MIP-1α, MIP-1β, MIP-3α, TNF-α, Fractalkine, GM-CSF, IFNγ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p70), IL-13	H	Mplex	Luminex xMAP

描述
产品目录编号	HSTCMAG28SPMX21
商名	MILLIPLEX
描述	MILLIPLEX MAP Human High Sensitivity T Cell Panel Premixed 21-plex - Immunology Multiplex Assay
背景信息	Cytokines are immunomodulatory polypeptides that play key roles in both adaptive and innate immune responses. A generic term, “cytokines” includes myokines (produced by muscle cells), lymphokines (produced by activated Th cells), interleukins (acting as mediators between T cells) and chemokines (responsible for T-cell migration). One of the regulatory mechanisms of the immune system, cytokines act at the recognition, activation, or effector phases of an immune response, modulating the development and functional activities of the subtypes of T cells, B cells and myeloid cells. Consequently, research involving cytokines plays a significant role in achieving a deeper understanding of the immune system and its multi-faceted response to most antigens, especially those responses that make up the inflammatory process. Low levels of inflammation are involved in many clinical and sub-clinical disease states, such as autoimmune disease, cardiovascular disease, diabetes, neurological disorders and cancer. Measuring picogram levels of cytokines, therefore, is critical for understanding the pathogenesis of these diseases.

产品信息
检测方法	Luminex xMAP
配置	Premixed
精度（%）	Intra-assay: <10% Inter-assay: <15%
板面类型	MAGNETIC Cytokines/Chemokines

应用
应用	The analytes available for this multiplex kit are: Fractalkine, GM-CSF, IFNγ, IL-1 β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p70), IL-13, IL-17A, IL-21, IL-23, ITAC, MIP-1α, MIP-1β, MIP-3α, TNFα.
主要应用	Multiplexing
应用说明	• This is an overnight incubation. • Because there are unique features concerning sample prep and assay set-up, please read the entire protocol before running the assay. These features are summarized on the next page. • This kit may be used for the analysis of all or any combination of the Human High Sensitivity T Cell panel analytes in serum, plasma or tissue/cell lysate and culture supernatant.

生物信息
品种反应性	Human
可用的分析物	IL-17A IL-21 IL-23 ITAC MIP-1α MIP-1β MIP-3α TNF-α Fractalkine GM-CSF IFNγ IL-1β IL-2 IL-4 IL-5 IL-6 IL-7 IL-8 IL-10 IL-12 (p70) IL-13
交叉反应性	There is no detectable cross-reactivity within the panel.
准确度	98% – 107%

理化信息
灵敏度	Please see kit protocol for individual assay sensitivities. 0.11 - 8.17 pg/mL (Overnight Incubation minDC)
稀释的线性	1:8 113.1%1:4 111.0%
标准曲线范围	TNFα: 0.45 – 1,750 pg/mL Fractalkine: 18.3 – 75,000 pg/mL GM-CSF: 1.22 – 5,000 pg/mL IFNγ: 0.61 – 2,500 pg/mL IL-1β: 0.49 – 2,000 pg/mL IL-2: 0.49 – 2,000 pg/mL IL-4: 1.83 – 7,500 pg/mL IL-5: 0.49 – 2,000 pg/mL IL-6: 0.18 – 750 pg/mL IL-7: 0.37 – 1,500 pg/mL IL-8: 0.31 – 1,250 pg/mL IL-10: 1.46 – 6,000 pg/mL IL-12 (p70): 0.49 – 2,000 pg/mL IL-13: 0.24 – 1,000 pg/mL IL-17A: 0.73 – 3,000 pg/mL IL-21: 0.24 – 1,000 pg/mL IL-23: 7.93 – 32,500 pg/mL ITAC: 1.46 – 6,000 pg/mL MIP-1α: 0.31 – 1,250 pg/mL MIP-1β: 0.92 – 3,750 pg/mL MIP-3α: 0.61 – 2,500 pg/mL

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Recommended storage for kit components is 2 - 8°C.

包装信息
数量	96-well plate

merck millipore,默克密理博,HSTCMAG28SPMX21,MILLIPLEX MAP Human High Sensitivity T Cell Panel Premixed 21-plex - Immunology Multiplex Assay

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