merck millipore,默克密理愽
  • merck millipore,默克密理博,676494,VEGF Inhibitor, Je-11 - Calbiochem

  • merck millipore,默克密理博,676494,VEGF Inhibitor, Je-11 - Calbiochem

    产品名称：VEGF Inhibitor, Je-11 - Calbiochem
    产品型号：676494
    The VEGF Inhibitor, Je-11 controls the biological activity of VEGF. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,676494,VEGF Inhibitor, Je-11 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,676494,VEGF Inhibitor, Je-11 - Calbiochem

    重要规格表

    经验配方
    C₁₈₈H₂₇₃N₄₉O₅₇
    描述
    概述 A dimerized peptide derived from the third Ig-like domain of the human vascular endothelial growth factor receptor-2 (VEGFR-2 or KDR/Flk-1) comprising residues 247 - 261. Acts as an inhibitor of VEGF-stimulated autophosphorylation of VEGFR-2 and inhibits the proliferation and migration of cultured microvascular endothelial cells. Binds to VEGF and blocks its interaction with VEGFR-2 (IC50 = 500 nM on extracellular VEGFR-2 fragments; IC50 = 30 µM on HUVEC).
    产品目录编号 676494
    品牌系列 Calbiochem®
    同义词 (RTELNVGIDFNWEYPAS)₂K-NH₂, VEGFR Tyrosine Kinase Inhibitor XI, VEGFR2 Kinase Inhibitor XII
    参考
    参考 Piossek, C., et al. 1999. J. Biol. Chem. 274, 5612.
    产品信息
    具有ATP竞争性 N
    形式 White lyophilized solid
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₁₈₈H₂₇₃N₄₉O₅₇
    化学配方 C₁₈₈H₂₇₃N₄₉O₅₇
    Molar Mass 4131.5
    吸湿 Hygroscopic
    肽序列 (H-Arg-Thr-Glu-Leu-Asn-Val-Gly-Ile-Asp-Phe-Asn-Trp-Glu-Tyr-Pro-Ala-Ser)₂-Lys-NH₂
    可逆 N
    生物信息
    主靶 Binds to VEGF and blocks its interaction with VEGFR-2
    主靶IC50 500 nM on extracellular VEGFR-2 fragments; 30 µM on HUVEC
    纯度 ≥90% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    肽序列 (H-Arg-Thr-Glu-Leu-Asn-Val-Gly-Ile-Asp-Phe-Asn-Trp-Glu-Tyr-Pro-Ala-Ser)₂-Lys-NH₂
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,676494,VEGF Inhibitor, Je-11 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,262015,DNA Base Excision Repair Pathway Inhibitor - CAS 6960-45-8 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,AB1722,Anti-Bcl-2 Antibody, a.a. 68-86 of mBCL2


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