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描述 产品目录编号 AG372 品牌系列 Chemicon®
商名 - Chemicon
描述 Glutamate Transporter, control peptide for MAB1587 概述 Glutamate Transporter (EAAC1) control peptide. Alternate Names - EAAC1
产品信息 演示 BSA-EDAC conjugated peptide. Liquid. 应用 主要应用 - Cell Function Assay
应用说明 Antibody blocking (MAB1587)
Optimal working concentration must be determined by the end user.生物信息 浓缩 1 mg/mL 品种 Rat Entrez基因编号 - NM_004170.4
基因符号 - EAAT3
- SLC1A1
- EAAC1
UniProt编号 - P43005
UniProt汇总 FUNCTION: SwissProt: P43005 # Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5 (By similarity).
SIZE: 524 amino acids; 57100 Da
SUBUNIT: Interacts with ARL6IP5/PRAF3 (By similarity).
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in all tissues tested including liver, muscle, testis, ovary, retinoblastoma cell line, neurons and brain (in which there was dense expression in substantia nigra, red nucleus, hippocampus and in cerebral cortical layers).
PTM: Glycosylated.
DISEASE: SwissProt: P43005 # Defects in SLC1A1 may be a cause of dicarboxylicamino aciduria [MIM:222730]; also known as glutamate-aspartate transport defect. This is as defect in renal and probably intestinal transport of glutamic and aspartic acids and is associated with moderate hyperprolinemia.
SIMILARITY: SwissProt: P43005 ## Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,MABE114,Anti-LSD1 Antibody, clone 3D12
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