- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,09-864,Anti-JHDM1B Antibody
产品名称：Anti-JHDM1B Antibody
产品型号：09-864
Anti-JHDM1B Antibody is a rabbit polyclonal antibody for detection of JHDM1B also known as lysine (K)-specific demethylase 2B, F-box protein FBL10, [Histone-H3]-lysine-36 demethylase 1B & has been val More>>
merck millipore,默克密理博,09-864,Anti-JHDM1B Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 09-864 描述 Anti-JHDM1B Antibody Alternate Names - CXXC-type zinc finger protein 2
- JMJD
- lysine (K)-specific demethylase 2B
- F-box protein FBL10
- [Histone-H3]-lysine-36 demethylase 1B
- JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein
- F-box and leucine-rich repeat protein 10
- protein containing CXXC domain 2
- jumonji C domain-containing histone demethylase 1B
- Jumonji domain-containing EMSY-interactor methyltransferase motif protein
- lysine-specific demethylase 2B
- Protein-containing CXXC domain 2
- JmjC domain-containing histone demethylation protein 1B
- Protein JEMMA
- F-box/LRR-repeat protein 10
背景信息 JmjC domain-containing histone demethylation protein 1B, also known as Lysine-specific demethylase 2B, is a nuclear enzyme encoded by the JHDM1B gene (also known as KDM2B) in human. JHDM1A/KDM2B exhibits H3K36-specific demethylase activity with a preference for H3K36me2 over H3K36me and H3K36me3 (PMID 16362057). JHDM1A/KDM2B is also reported to negatively regulate cell proliferation by targeting rDNA and thereby repressing the transcription of rRNA in a JmjC-domain-dependent manner (PMID 17994099). 产品信息 格式 Affinity Purified 控制 - HeLa nuclear extract
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-JHDM1B Antibody is a rabbit polyclonal antibody for detection of JHDM1B also known as lysine (K)-specific demethylase 2B, F-box protein FBL10, [Histone-H3]-lysine-36 demethylase 1B & has been validated in WB, ICC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected JHDM1B in NIH/3T3 and HeLa cells.
Immunocytochemistry Analysis: 2 µg/mL from a representative lot detected JHDM1B in A431 cells.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human JHDM1B. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 RatHumanMouse Species Reactivity Note Human, Mouse, Rat. Predicted to react with Rabbit, Chimpanzee, Horse, and Porcine based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_115979
Entrez基因汇总 This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq]. 基因符号 - FBL10
- KDM2B
- CXXC2
- FBXL10
- JHDM1B
- PCCX2
- Fbl10
纯化方法 Affinity purified UniProt编号 - Q8NHM5
产品使用声明 质量保证 Evaluated by Western Blot in HeLa nuclear extract.
Western Blot Analysis: 1 µg/mL of this antibody detected JHDM1B on 10 µg of HeLa nuclear extract.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,662065,Ubiquitin, Methylated, Human, Recombinant
下一件merck millipore产品：merck millipore,默克密理博,ABC158,Anti-p53 Upregulated Modulator of Apoptosis (PUMA) Antibody
相关产品
merck millipore,默克密理博,ABC263,Anti-CDC45 Antibody
merck millipore,默克密理博,MABN140,Anti-NeuN (rabbit monoclonal) Antibody, clone 27-4
merck millipore,默克密理博,648490,TRPC3 Channel Inhibitor, Pyr3 - CAS 1160514-60-2 - Calbiochem
merck millipore,默克密理博,662065,Ubiquitin, Methylated, Human, Recombinant
merck millipore,默克密理博,ABC158,Anti-p53 Upregulated Modulator of Apoptosis (PUMA) Antibody
merck millipore,默克密理博,05-235,Anti-EF1α Antibody, clone CBP-KK1
merck millipore,默克密理博,565789,γ-Secretase Inhibitor XX - CAS 209984-56-5 - Calbiochem
merck millipore,默克密理博,06-229,Anti-phospho-erbB-2/HER-2 (Tyr1248) Antibody
merck millipore,默克密理博,AG372,Glutamate Transporter, control peptide for MAB1587